SYNTHESIS OF CEPHALOSPORINS HAVING A HETEROCYCLIC GROUP AT THE C-3 POSITION

被引：0

作者：

JUNG, MH ^{[1
]}

CHO, KW ^{[1
]}

KIM, WJ ^{[1
]}

SHIN, JS ^{[1
]}

PARK, CS ^{[1
]}

机构：

[1] YUNGJIN PHARM CO LTD,KYUNGGI-DO 456860,SOUTH KOREA

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 1993年 / 14卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-(3-Bromotetrahydrofuran-2-yl)-3-cephem 7 was obtained from 3-(2-hydroxyethyl)vinyl-3-cephem 6 by the cyclization reaction using N-bromosuccinimide. Compound 5 was prepared by Wittig reaction, namely a coupling of cephem-derived triphenylphosphonium salt 3 with aldehyde component 4 in the presence of base.

引用

页码：32 / 34

页数：3

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