SYNTHESIS OF CEPHALOSPORINS HAVING A HETEROCYCLIC GROUP AT THE C-3 POSITION

被引：0
|
作者：
JUNG, MH [1 ]
CHO, KW [1 ]
KIM, WJ [1 ]
SHIN, JS [1 ]
PARK, CS [1 ]
机构：
[1] YUNGJIN PHARM CO LTD,KYUNGGI-DO 456860,SOUTH KOREA
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 1993年 / 14卷 / 01期
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D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
3-(3-Bromotetrahydrofuran-2-yl)-3-cephem 7 was obtained from 3-(2-hydroxyethyl)vinyl-3-cephem 6 by the cyclization reaction using N-bromosuccinimide. Compound 5 was prepared by Wittig reaction, namely a coupling of cephem-derived triphenylphosphonium salt 3 with aldehyde component 4 in the presence of base.
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页码：32 / 34
页数：3
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