Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

被引:0
|
作者
Ilya M. Flyamer
Johanna Gassler
Maxim Imakaev
Hugo B. Brandão
Sergey V. Ulianov
Nezar Abdennur
Sergey V. Razin
Leonid A. Mirny
Kikuë Tachibana-Konwalski
机构
[1] IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences,Department of Physics
[2] Vienna Biocenter (VBC),undefined
[3] Institute of Gene Biology,undefined
[4] Russian Academy of Sciences,undefined
[5] Faculty of Biology,undefined
[6] Lomonosov Moscow State University,undefined
[7] Institute for Medical Engineering and Science,undefined
[8] Massachusetts Institute of Technology (MIT),undefined
[9] Massachusetts Institute of Technology (MIT),undefined
[10] Harvard Program in Biophysics,undefined
[11] Harvard University,undefined
[12] Computational and Systems Biology Program,undefined
[13] Massachusetts Institute of Technology (MIT),undefined
[14] ,undefined
[15] †Present address: MRC Human Genetics Unit,undefined
[16] Institute of Genetics and Molecular Medicine,undefined
[17] University of Edinburgh,undefined
[18] Edinburgh EH4 2XU,undefined
[19] UK.,undefined
来源
Nature | 2017年 / 544卷
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摘要
Using a single-nucleus Hi-C protocol, the authors find that spatial organization of chromatin during oocyte-to-zygote transition differs between paternal and maternal nuclei within a single-cell zygote.
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页码:110 / 114
页数:4
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