Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

被引：0

作者：

Ilya M. Flyamer

Johanna Gassler

Maxim Imakaev

Hugo B. Brandão

Sergey V. Ulianov

Nezar Abdennur

Sergey V. Razin

Leonid A. Mirny

Kikuë Tachibana-Konwalski

机构：

[1] IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences,Department of Physics

[2] Vienna Biocenter (VBC),undefined

[3] Institute of Gene Biology,undefined

[4] Russian Academy of Sciences,undefined

[5] Faculty of Biology,undefined

[6] Lomonosov Moscow State University,undefined

[7] Institute for Medical Engineering and Science,undefined

[8] Massachusetts Institute of Technology (MIT),undefined

[9] Massachusetts Institute of Technology (MIT),undefined

[10] Harvard Program in Biophysics,undefined

[11] Harvard University,undefined

[12] Computational and Systems Biology Program,undefined

[13] Massachusetts Institute of Technology (MIT),undefined

[14] ,undefined

[15] †Present address: MRC Human Genetics Unit,undefined

[16] Institute of Genetics and Molecular Medicine,undefined

[17] University of Edinburgh,undefined

[18] Edinburgh EH4 2XU,undefined

[19] UK.,undefined

来源：

Nature | 2017年 / 544卷

关键词：

D O I：

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学科分类号：

摘要：

Using a single-nucleus Hi-C protocol, the authors find that spatial organization of chromatin during oocyte-to-zygote transition differs between paternal and maternal nuclei within a single-cell zygote.

引用

页码：110 / 114

页数：4

共 47 条

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[42] Single-cell Hi-C bridges microscopy and genome-wide sequencing approaches to study 3D chromatin organization
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[47] Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation (vol 21, pg 432, 2018)
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