Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell

被引:0
|
作者
Takashi Nagano
Yaniv Lubling
Eitan Yaffe
Steven W Wingett
Wendy Dean
Amos Tanay
Peter Fraser
机构
[1] Nuclear Dynamics Programme,Department of Computer Science and Applied Mathematics and Department of Biological Regulation
[2] The Babraham Institute,undefined
[3] Weizmann Institute,undefined
[4] Epigenetics Programme,undefined
[5] The Babraham Institute,undefined
来源
Nature Protocols | 2015年 / 10卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The Fraser laboratory provides a protocol for performing Hi-C on single cells. The technique is an important step towards understanding cellular variability in genome organization and chromosome conformation.
引用
收藏
页码:1986 / 2003
页数:17
相关论文
共 50 条
  • [1] Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell
    Nagano, Takashi
    Lubling, Yaniv
    Yaffe, Eitan
    Wingett, Steven W.
    Dean, Wendy
    Tanay, Amos
    Fraser, Peter
    [J]. NATURE PROTOCOLS, 2015, 10 (12) : 1986 - 2003
  • [2] scHiCDiff: detecting differential chromatin interactions in single-cell Hi-C data
    Liu, Huiling
    Ma, Wenxiu
    [J]. BIOINFORMATICS, 2023, 39 (10)
  • [3] Single-cell Hi-C bridges microscopy and genome-wide sequencing approaches to study 3D chromatin organization
    Ulianov, Sergey V.
    Tachibana-Konwalski, Kikue
    Razin, Sergey V.
    [J]. BIOESSAYS, 2017, 39 (10)
  • [4] Massively multiplex single-cell Hi-C
    Ramani, Vijay
    Deng, Xinxian
    Qiu, Ruolan
    Gunderson, Kevin L.
    Steemers, Frank J.
    Disteche, Christine M.
    Noble, William S.
    Duan, Zhijun
    Shendure, Jay
    [J]. NATURE METHODS, 2017, 14 (03) : 263 - +
  • [5] Massively multiplex single-cell Hi-C
    Ramani V.
    Deng X.
    Qiu R.
    Gunderson K.L.
    Steemers F.J.
    Disteche C.M.
    Noble W.S.
    Duan Z.
    Shendure J.
    [J]. Nature Methods, 2017, 14 (3) : 263 - 266
  • [6] Single-cell technologies meet Hi-C
    Hughes, Jim R.
    Davies, James O. J.
    [J]. NATURE GENETICS, 2024, : 1542 - 1543
  • [7] Unsupervised embedding of single-cell Hi-C data
    Liu, Jie
    Lin, Dejun
    Yardimci, Galip Gurkan
    Noble, William Stafford
    [J]. BIOINFORMATICS, 2018, 34 (13) : 96 - 104
  • [8] Genome-wide Hi-C analysis reveals extensive hierarchical chromatin interactions in rice
    Dong, Qianli
    Li, Ning
    Li, Xiaochong
    Yuan, Zan
    Xie, Dejian
    Wang, Xiaofei
    Li, Jianing
    Yu, Yanan
    Wang, Jinbin
    Ding, Baoxu
    Zhang, Zhibin
    Li, Changping
    Bian, Yao
    Zhang, Ai
    Wu, Ying
    Liu, Bao
    Gong, Lei
    [J]. PLANT JOURNAL, 2018, 94 (06): : 1141 - 1156
  • [9] Genome-wide Hi-C analysis reveals extensive hierarchical chromatin interactions in rice
    Key Laboratory of Molecular Epigenetics of the Ministry of Education , Northeast Normal University, Changchun
    130024, China
    不详
    100176, China
    [J]. Plant J., 1600, 6 (1141-1156):
  • [10] Single-cell Hi-C discloses general principles of the individual genome folding in Drosophila
    Zakharova, V. S.
    Galitsyna, A. A.
    Polovnikov, K. E.
    Khrameeva, E. E.
    Logacheva, M. D.
    Mikhaleva, E. A.
    Vassetzky, E. S.
    Gavrilov, A. A.
    Shevelev, Y. Y.
    Nechaev, S. K.
    Ulianov, S. V.
    Razin, S. V.
    [J]. FEBS OPEN BIO, 2018, 8 : 65 - 66