Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell

被引:0
|
作者
Takashi Nagano
Yaniv Lubling
Eitan Yaffe
Steven W Wingett
Wendy Dean
Amos Tanay
Peter Fraser
机构
[1] Nuclear Dynamics Programme,Department of Computer Science and Applied Mathematics and Department of Biological Regulation
[2] The Babraham Institute,undefined
[3] Weizmann Institute,undefined
[4] Epigenetics Programme,undefined
[5] The Babraham Institute,undefined
来源
Nature Protocols | 2015年 / 10卷
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学科分类号
摘要
The Fraser laboratory provides a protocol for performing Hi-C on single cells. The technique is an important step towards understanding cellular variability in genome organization and chromosome conformation.
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页码:1986 / 2003
页数:17
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