Let V(G) and E(G) be, respectively, the vertex set and edge set of a graph G. The general sum-connectivity index of a graph G is denoted by χα(G)\documentclass[12pt]{minimal}
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\begin{document}$$\chi _\alpha (G)$$\end{document} and is defined as ∑uv∈E(G)(du+dv)α\documentclass[12pt]{minimal}
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\begin{document}$$\sum \limits _{uv\in E(G)}(d_u+d_v)^\alpha $$\end{document}, where uv is an edge that connect the vertices u,v∈V(G)\documentclass[12pt]{minimal}
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\begin{document}$$u,v\in V(G)$$\end{document}, du\documentclass[12pt]{minimal}
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\begin{document}$$d_u$$\end{document} is the degree of a vertex u and α\documentclass[12pt]{minimal}
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\begin{document}$$\alpha $$\end{document} is any non-zero real number. A cactus is a graph in which any two cycles have at most one common vertex. Let Cn,t\documentclass[12pt]{minimal}
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\begin{document}$$\mathscr {C}_{n,t}$$\end{document} denote the class of all cacti with order n and t pendant vertices. In this paper, a maximum general sum-connectivity index (χα(G)\documentclass[12pt]{minimal}
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\begin{document}$$\chi _\alpha (G)$$\end{document}, α>1\documentclass[12pt]{minimal}
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\begin{document}$$\alpha >1$$\end{document}) of a cacti graph with order n and t pendant vertices is considered. We determine the maximum general sum-connectivity index of n-vertex cacti graph. Based on our obtained results, we characterize the cactus with a perfect matching having the maximum general sum-connectivity index.
