LiClO4-Catalysed C-alkylation of pyrrole and indoles with aziridines and epoxides

被引：0
|
作者：
Yadav, JS [1 ]
Reddy, BVS [1 ]
Parimala, G [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India
来源：
JOURNAL OF CHEMICAL RESEARCH | 2003年 / 02期
关键词：
lithium perchlorate; lithium triflate; aziridines; C-alkylation; sulfonamides; pyrroles; indoles;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aryl-N-tosylaziridines and epoxides smoothly undergo ring-opening with pyrrole and indoles in the presence of 5M lithium perchlorate in diethyl ether (LPDE) at ambient temperature to afford the corresponding 2- and 3-alkylated pyrroles and 3-alkylated indoles in high yields with high selectivity. LiOTf is also found to be an effective catalyst for this transformation.
引用
收藏
页码：78 / 81
页数：4
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