LiClO4-Catalysed C-alkylation of pyrrole and indoles with aziridines and epoxides

被引：0

作者：

Yadav, JS ^{[1
]}

Reddy, BVS ^{[1
]}

Parimala, G ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India

来源：

JOURNAL OF CHEMICAL RESEARCH | 2003年 / 02期

关键词：

lithium perchlorate; lithium triflate; aziridines; C-alkylation; sulfonamides; pyrroles; indoles;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Aryl-N-tosylaziridines and epoxides smoothly undergo ring-opening with pyrrole and indoles in the presence of 5M lithium perchlorate in diethyl ether (LPDE) at ambient temperature to afford the corresponding 2- and 3-alkylated pyrroles and 3-alkylated indoles in high yields with high selectivity. LiOTf is also found to be an effective catalyst for this transformation.

引用

页码：78 / 81

页数：4

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