Synthesis, and biological evaluation of some 4-thiazolidinones

被引：0
|
作者：
Amir, M [1 ]
Azam, F [1 ]
机构：
[1] Hamdard Univ, Fac Pharm, Dept Pharmaceut Chem, New Delhi 110062, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2004年 / 14卷 / 02期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis and biological activities (antiinflammatory, antibacterial and antifungal) of a number of 2,3-substituted 4-thiazolidinone derivatives are described. The compounds showed antiinflammatory activity ranging from 61.53% to 83.07% whereas reference drug ibuprofen showed 83.07% inhibition at 100 mg/kg oral dose in this test. All these compounds showed significant antibacterial and antifungal activity when compared with standard drugs amikacin and fluconazole.
引用
收藏
页码：119 / 122
页数：4
相关论文
共 50 条
  • [41] Synthesis and biological evaluation of some new azetidinones and thiazolidinones
    Modha, JJ
    Parmar, JM
    Datta, NJ
    Parekh, HH
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2002, 41 (12): : 2694 - 2697
  • [42] Synthesis and biological evaluation of some thiazolidinones as antimicrobial agents
    Patel, Divyesh
    Kumari, Premlata
    Patel, Navin
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 48 : 354 - 362
  • [43] Synthesis of some new 4-thiazolidinones and thiazin-4-ones as biologically potent agents
    Gadre, J. N.
    Nair, Smita
    Chitre, Saurabh
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2007, 46 (04): : 653 - 659
  • [44] SYNTHESIS OF 4-THIAZOLIDINONES FROM RHODANINES BY THIOCARBONYL REMOVAL
    HANSEN, MM
    HARKNESS, AR
    TETRAHEDRON LETTERS, 1994, 35 (38) : 6971 - 6974
  • [45] Synthesis of new pyrazolothiazole derivatives from 4-thiazolidinones
    Turgut, Zuhal
    Yolacan, Cigdem
    Aydogan, Feray
    Bagdatli, Emine
    Ocal, Nuket
    MOLECULES, 2007, 12 (09): : 2151 - 2159
  • [46] Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds
    Küçükgüzel, SG
    Oruç, EE
    Rollas, S
    Sahin, F
    Özbek, A
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2002, 37 (03) : 197 - 206
  • [47] Microwave induced synthesis of 4-thiazolidinones as antimicrobial agents
    Khatri, BL
    Trivedi, AM
    Sodha, VA
    Hirpara, HM
    Parekh, HH
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2002, 12 (02) : 175 - 176
  • [48] SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME 2-ARYL-3-SUBSTITUTED 4-THIAZOLIDINONES
    CESUR, N
    CESUR, Z
    ERGENC, N
    UZUN, M
    KIRAZ, M
    KASIMOGLU, O
    KAYA, D
    ARCHIV DER PHARMAZIE, 1994, 327 (04) : 271 - 272
  • [49] Synthesis of some novel fluorinated 4-thiazolidinones containing amide linkages and their antimicrobial screening
    Shah, Tejaskumar J.
    Desai, Vikas A.
    ARKIVOC, 2007, : 218 - 228
  • [50] Progress in the chemistry of 4-thiazolidinones
    Hamama, Wafaa S.
    Ismail, Mohamed A.
    Shaaban, Saad
    Zoorob, Hanafi H.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 45 (04) : 939 - 956
12345