SYNTHESIS OF 4-THIAZOLIDINONES FROM RHODANINES BY THIOCARBONYL REMOVAL

被引：10
|
作者：
HANSEN, MM
HARKNESS, AR
机构：
[1] Chemical Process Research and Development Division Lilly Research Labs. A Division of Eli Lilly, Company Indianapolis
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 38期
关键词：
D O I：
10.1016/0040-4039(94)88201-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new procedure for synthesis of 4-thiazolidinones from readily available rhodanines is reported. Slow addition of the substrate to excess zinc dust in acetic acid at reflux affords the best yields. Identification of dimeric byproducts led to development of a procedure to suppress their formation.
引用
收藏
页码：6971 / 6974
页数：4
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