Triple channel analysis of Gafchromic EBT3 irradiated with clinical carbon-ion beams

被引:7
|
作者
Holm, Kim Marina [1 ,2 ,3 ,4 ]
Yukihara, Eduardo G. [5 ]
Ahmed, Md Foiez [6 ]
Greilich, Steffen [2 ,3 ]
Jaekel, Oliver [2 ,3 ,7 ]
机构
[1] Phys Tech Bundesanstalt PTB, Dept Dosimetry Radiat Therapy & Diagnost Radiol, Bundesallee 100, D-38116 Braunschweig, Germany
[2] German Canc Res Ctr, Dept Med Phys Radiat Oncol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany
[3] Heidelberg Inst Radiat Oncol HIRO, Heidelberg, Germany
[4] Heidelberg Univ, Dept Phys & Astron, Neuenheimer Feld 226, D-69120 Heidelberg, Germany
[5] Paul Scherrer Inst, Dept Radiat Safety & Secur, Forschungsstr 111, CH-5232 Villigen, Switzerland
[6] Sun Nucl Corp, 3275 Suntree Blvd, Melbourne, FL 32940 USA
[7] Univ Hosp Heidelberg, Heidelberg Ion Beam Therapy Ctr HIT, Neuenheimer Feld 450, D-69120 Heidelberg, Germany
关键词
Triple channel analysis; Gafchromic EBT3; Carbon-ion beams; RADIOCHROMIC FILM DOSIMETRY; PROTON;
D O I
10.1016/j.ejmp.2021.06.009
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Self-developing radiochromic film is widely used in radiotherapy QA procedures. To compensate for typical film inhomogeneities, the triple channel analysis method is commonly used for photon-irradiated film. We investigated the applicability of this method for GafchromicTMEBT3 (Ashland) film irradiated with a clinically used carbon-ion beam. Calibration curves were taken from EBT3 film specimens irradiated with monoenergetic carbon-ion beams of different doses. Measurements of the lateral field shape and homogeneity were performed in the middle of a passively modulated spread-out Bragg peak and compared to simultaneous characterization by means of a 2D ionization chamber array. Additional measurements to investigate the applicability of EBT3 for quality assurance (QA) measurement in carbon-ion beams were performed. The triple-channel analysis reduced the relative standard deviation of the doses in a uniform carbon ion field by 30% (from 1.9% to 1.3%) and reduced the maximum deviation by almost a factor of 3 (from 28.6% to 9.8%), demonstrating the elimination of film artifacts. The corrected film signal showed considerably improved image quality and quantitative agreement with the ionization chamber data, thus providing a clear rationale for the usage of the triple channel analysis in carbon-beam QA.
引用
收藏
页码:123 / 130
页数:8
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