Palladium catalyzed ligand-free Suzuki cross-coupling reactions of benzylic halides with aryl boronic acids under mild conditions

被引：81
|
作者：
Bandgar, BP [1 ]
Bettigeri, SV [1 ]
Phopase, J [1 ]
机构：
[1] Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Vishnupuri, Nanded, India
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 37期
关键词：
Suzuki cross-coupling reactions; catalyst; aryl boronic acids; benzylic halides; diarylmethanes;
D O I：
10.1016/j.tetlet.2004.07.073
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient Suzuki cross-coupling reaction between benzylic halides and aryl boronic acids using palladium chloride as catalyst in acetone:water (3:1) as the solvent system has been developed. High yields of products, mild reaction conditions and short reaction times in the absence of ligand are important features of this method. (C) 2004 Elsevier Ltd. All rights reserved.
引用
下载
收藏
页码：6959 / 6962
页数：4
相关论文
共 50 条
  • [31] Ligand-free palladium-catalyzed cyanation of aryl halides
    Weissman, SA
    Zewge, D
    Chen, C
    JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (04): : 1508 - 1510
  • [32] Palladium-Catalysed Cross-Coupling of Benzylammonium Salts with Boronic Acids under Mild Conditions
    Turtscher, Paul L.
    Davis, Holly J.
    Phipps, Robert J.
    SYNTHESIS-STUTTGART, 2018, 50 (04): : 793 - 802
  • [33] Palladium-Catalyzed Cross-Coupling of Electron-Poor Terminal Alkynes with Arylboronic Acids under Ligand-Free and Aerobic Conditions
    Zhou, Ming-Bo
    Wei, Wen-Ting
    Xie, Ye-Xiang
    Lei, Yong
    Li, Jin-Heng
    JOURNAL OF ORGANIC CHEMISTRY, 2010, 75 (16): : 5635 - 5642
  • [34] Cross-coupling reactions of aryl pivalates with boronic acids
    Quasdorf, Kyle W.
    Tian, Xia
    Garg, Neil K.
    1600, American Chemical Society, Columbus, OH 43210-3337, United States (130):
  • [35] Cross-Coupling Reactions of Aryl Pivalates with Boronic Acids
    Quasdorf, Kyle W.
    Tian, Xia
    Garg, Neil K.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (44) : 14422 - +
  • [36] Suzuki cross-coupling of aryl halides with aryl boronic acids catalyzed by phosphine-free NiCl2•6H2O
    Zim, D
    Monteiro, AL
    TETRAHEDRON LETTERS, 2002, 43 (22) : 4009 - 4011
  • [37] Ligand-free palladium-catalyzed decarboxylative coupling reactions of aryl iodides and alkynyl carboxylic acids
    Pyo, Ayoung
    Kim, Ji Dang
    Choi, Hyun Chul
    Lee, Sunwoo
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2013, 724 : 271 - 274
  • [38] CROSS-COUPLING REACTIONS OF MONOSUBSTITUTED ACETYLENES AND ARYL HALIDES CATALYZED BY PALLADIUM ON CHARCOAL
    DELAROSA, MA
    VELARDE, E
    GUZMAN, A
    SYNTHETIC COMMUNICATIONS, 1990, 20 (13) : 2059 - 2064
  • [39] Enantioselective Palladium-Catalyzed Cross-Coupling of α-Bromo Carboxamides and Aryl Boronic Acids
    Li, Bowen
    Li, Tiejun
    Aliyu, Muinat A.
    Li, Zhen Hua
    Tang, Wenjun
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (33) : 11355 - 11359
  • [40] Nano-CuO-Catalyzed Ullmann Coupling of Phenols with Aryl Halides under Ligand-Free Conditions
    Zhang, Jintang
    Zhang, Zuhui
    Wang, Ye
    Zheng, Xiaoqi
    Wang, Zhiyong
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2008, 2008 (30) : 5112 - 5116
12345