Palladium catalyzed ligand-free Suzuki cross-coupling reactions of benzylic halides with aryl boronic acids under mild conditions

被引:81
|
作者
Bandgar, BP [1 ]
Bettigeri, SV [1 ]
Phopase, J [1 ]
机构
[1] Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Vishnupuri, Nanded, India
关键词
Suzuki cross-coupling reactions; catalyst; aryl boronic acids; benzylic halides; diarylmethanes;
D O I
10.1016/j.tetlet.2004.07.073
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A highly efficient Suzuki cross-coupling reaction between benzylic halides and aryl boronic acids using palladium chloride as catalyst in acetone:water (3:1) as the solvent system has been developed. High yields of products, mild reaction conditions and short reaction times in the absence of ligand are important features of this method. (C) 2004 Elsevier Ltd. All rights reserved.
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页码:6959 / 6962
页数:4
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