Ligand-Free Copper-Catalyzed Cross-Coupling Reaction of Alkynes with Aryl Iodides and Vinyl Halides

被引：11
|
作者：
Tsai, Wan-Ting [1 ]
Lin, Yun-Yung [1 ]
Chen, Yi-An [1 ]
Lee, Chin-Fa [1 ]
机构：
[1] Natl Chung Hsing Univ, Dept Chem, Taichung 402, Taiwan
来源：
SYNLETT | 2014年 / 25卷 / 03期
关键词：
copper; cross-coupling; Sonogashira reaction; ligand-free; aryl iodide; vinyl halide; TERMINAL ALKYNES; PALLADIUM-FREE; SONOGASHIRA REACTION; HETEROARYL HALIDES; CHEMISTRY; ABSENCE;
D O I：
10.1055/s-0033-1340461
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A copper-catalyzed cross-coupling reaction of alkynes with aryl iodides is described. The system tolerates a broad range of functional groups and enables the sterically demanding substrates presented during the catalysis with only 5-10 mol% of Cu2O as the catalyst.
引用
收藏
页码：443 / 447
页数：5
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