Palladium catalyzed ligand-free Suzuki cross-coupling reactions of benzylic halides with aryl boronic acids under mild conditions

被引:81
|
作者
Bandgar, BP [1 ]
Bettigeri, SV [1 ]
Phopase, J [1 ]
机构
[1] Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Vishnupuri, Nanded, India
关键词
Suzuki cross-coupling reactions; catalyst; aryl boronic acids; benzylic halides; diarylmethanes;
D O I
10.1016/j.tetlet.2004.07.073
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A highly efficient Suzuki cross-coupling reaction between benzylic halides and aryl boronic acids using palladium chloride as catalyst in acetone:water (3:1) as the solvent system has been developed. High yields of products, mild reaction conditions and short reaction times in the absence of ligand are important features of this method. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:6959 / 6962
页数:4
相关论文
共 50 条
  • [41] Water-Soluble Palladium Nanoclusters as Catalysts in Ligand-Free Suzuki-Miyaura Cross-Coupling Reactions
    Karna, Priya
    Okeke, Micheal
    Meira, Debora Motta
    Finfrock, Zou
    Yang, Dong-Sheng
    ACS APPLIED NANO MATERIALS, 2022, 5 (03) : 3188 - 3193
  • [42] Ligand-Controlled Palladium-Catalyzed Regiodivergent Suzuki-Miyaura Cross-Coupling of Allylboronates and Aryl Halides
    Yang, Yang
    Buchwald, Stephen L.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (29) : 10642 - 10645
  • [43] Ligand-Free Cu-Catalyzed Suzuki Coupling of Alkynyl Bromides with Boronic Acids in Ethanol Under Microwave Irradiation
    Babu, Sheba Ann
    Saranya, Salim
    Rohit, K. R.
    Anilkumar, Gopinathan
    CHEMISTRYSELECT, 2019, 4 (03): : 1019 - 1022
  • [44] HECK VERSUS SUZUKI PALLADIUM-CATALYZED CROSS-COUPLING OF A VINYLBORONATE ESTER WITH ARYL HALIDES
    HUNT, AR
    STEWART, SK
    WHITING, A
    TETRAHEDRON LETTERS, 1993, 34 (22) : 3599 - 3602
  • [45] Recent advances in transition metal-catalysed cross-coupling of (hetero)aryl halides and analogues under ligand-free conditions
    Ayogu, Jude I.
    Onoabedje, Efeturi A.
    CATALYSIS SCIENCE & TECHNOLOGY, 2019, 9 (19) : 5233 - 5255
  • [46] Palladium-Catalyzed Cross-Coupling of Aryl Bromides and Chlorides with Trimethylsilylalkynes under Mild Conditions
    Tlahuext-Aca, Adrian
    Nguyen, Quyen D.
    Gao, Yang
    Sati, Girish C.
    Zhao, Jinpeng
    Valco, Daniel
    JOURNAL OF ORGANIC CHEMISTRY, 2024, 89 (18): : 13762 - 13767
  • [47] Palladium-free and ligand-free Sonogashira cross-coupling
    Thathagar, MB
    Beckers, J
    Rothenberg, G
    GREEN CHEMISTRY, 2004, 6 (04) : 215 - 218
  • [48] Ligand-Promoted Oxidative Cross-Coupling of Aryl Boronic Acids and Aryl Silanes by Palladium Catalysis
    Yu, Jingxun
    Liu, Jun
    Shi, Guangfa
    Shao, Changdong
    Zhang, Yanghui
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (13) : 4079 - 4082
  • [49] Efficient and ligand free palladium catalyst for Suzuki and Heck cross-coupling reactions
    Luo Bin
    Wang JiaQing
    Ge DanHua
    Li XinMing
    Cao XueQin
    Pan Yue
    Gu HongWei
    SCIENCE CHINA-CHEMISTRY, 2014, 57 (09) : 1310 - 1314
  • [50] Efficient and ligand free palladium catalyst for Suzuki and Heck cross-coupling reactions
    LUO Bin
    WANG JiaQing
    GE DanHua
    LI XinMing
    CAO XueQin
    PAN Yue
    GU HongWei
    Science China Chemistry, 2014, (09) : 1310 - 1314