CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data

被引:4
|
作者
Bollen, Sander [1 ,2 ]
Leddin, Mathias [3 ]
Andrade-Navarro, Miguel A. [1 ]
Mah, Nancy [1 ]
机构
[1] Max Delbruck Ctr Mol Med, Computat Biol & Data Min Grp, D-13125 Berlin, Germany
[2] Univ Utrecht, Grad Sch Life Sci, NL-3584 CG Utrecht, Netherlands
[3] Roche Diagnost GmbH, D-82377 Penzberg, Germany
关键词
STEM-CELLS;
D O I
10.1093/bioinformatics/btu028
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The current methods available to detect chromosomal abnormalities from DNA microarray expression data are cumbersome and inflexible. CAFE has been developed to alleviate these issues. It is implemented as an R package that analyzes Affymetrix*. CEL files and comes with flexible plotting functions, easing visualization of chromosomal abnormalities.
引用
收藏
页码:1484 / 1485
页数:2
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