An Efficient Synthesis of Pyrido[2,3-d][6,5-d]dipyrimidine and 5,5′-Arylmethylenebis(2,6-diaminopyrimidinone) Derivatives under Microwave Irradiation

被引：4

作者：

Lin, Zhilan ^{[1
]}

Hu, Huiling ^{[1
]}

You, Xinkui ^{[1
]}

Zhang, Xueli ^{[1
]}

Gao, Yuan ^{[1
]}

机构：

[1] Shenzhen Univ, Coll Chem & Chem Engn, Shenzhen 518060, Guangdong, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷 / 01期

基金：

中国国家自然科学基金;

关键词：

DIHYDROFOLATE REDUCTASES; PNEUMOCYSTIS-CARINII; TOXOPLASMA-GONDII; CRYSTAL-STRUCTURE; ANTITUMOR AGENTS; INHIBITORS; PYRIMIDINES; CHEMISTRY; ANALOGS; HEPT;

D O I：

10.1002/jhet.1647

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrido[2,3-d][6,5-d]dipyrimidine and 5,5-arylmethylenebis(2,6-diaminopyrimidinone) derivatives have been synthesized through a rapid reaction of aromatic aldehydes with aminopyrimidines in acetic acid under microwave irradiation. This method has the advantages of simple operation, high yields, short reaction time, and easy work-up.

引用

页码：277 / 281

页数：5

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