An Efficient Synthesis of Pyrido[2,3-d][6,5-d]dipyrimidine and 5,5′-Arylmethylenebis(2,6-diaminopyrimidinone) Derivatives under Microwave Irradiation

被引：4

作者：

Lin, Zhilan ^{[1
]}

Hu, Huiling ^{[1
]}

You, Xinkui ^{[1
]}

Zhang, Xueli ^{[1
]}

Gao, Yuan ^{[1
]}

机构：

[1] Shenzhen Univ, Coll Chem & Chem Engn, Shenzhen 518060, Guangdong, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷 / 01期

基金：

中国国家自然科学基金;

关键词：

DIHYDROFOLATE REDUCTASES; PNEUMOCYSTIS-CARINII; TOXOPLASMA-GONDII; CRYSTAL-STRUCTURE; ANTITUMOR AGENTS; INHIBITORS; PYRIMIDINES; CHEMISTRY; ANALOGS; HEPT;

D O I：

10.1002/jhet.1647

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrido[2,3-d][6,5-d]dipyrimidine and 5,5-arylmethylenebis(2,6-diaminopyrimidinone) derivatives have been synthesized through a rapid reaction of aromatic aldehydes with aminopyrimidines in acetic acid under microwave irradiation. This method has the advantages of simple operation, high yields, short reaction time, and easy work-up.

引用

页码：277 / 281

页数：5

共 50 条

[21] PYRIDO[2,3-D]PYRIMIDINES AND PYRIDO[2,3-D-6,5-D']DIPYRIMIDINES AS POTENTIAL CHEMOTHERAPEUTIC-AGENTS .8.
RAM, VJ
VANDENBERGHE, DA
VLIETINCK, AJ
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (01) : 217 - 219
[22] Microwave-Assisted Rapid Synthesis of Pyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetraones over Sulfonic Acid Functionalized Imidazolium Salts under Solvent-Free Condition
Saikia, Lakhinath
Namsa, Nima. D.
Thakur, A. J.
CHEMISTRYSELECT, 2017, 2 (25): : 7553 - 7557
[23] Synthesis and Cytotoxic Activity of Some Novel Thieno [2,3-d:4,5-d′] Dipyrimidine Derivatives
El-Sayed, Elsherbiny Hamdy
Fadda, Ahmed Ali
ACTA CHIMICA SLOVENICA, 2018, 65 (04) : 853 - 864
[24] Vitamin C as an efficient and green homogeneous catalyst for the synthesis of pyride[2,3-d:5,6-d′] dipyrimidine derivatives
Yaghoobi, Morteza
Karimipour-saryazdi, Amir
Ghasemzadeh, Mohammad Ali
IRANIAN JOURNAL OF CATALYSIS, 2024, 14 (03):
[25] A FACILE ENTRY TO FUSED PYRIMIDINES - PREPARATION OF PYRIMIDO[4,5-B]QUINOLINE AND PYRIDO[2,3-D-6,5-D']DIPYRIMIDINE DERIVATIVES
MOLINA, P
VILAPLANA, MJ
PASTOR, A
SYNTHESIS-STUTTGART, 1992, (09): : 827 - 829
[26] Pyrido[2,3-d]pyrimidines and pyrimido[5′4′:5,6]pyrido[2,3-d]pyrimidines as new antiviral agents:: Synthesis and biological activity
Nasr, MN
Gineinah, MM
ARCHIV DER PHARMAZIE, 2002, 335 (06) : 289 - 295
[27] Effective and Rapid Synthesis of Pyrido[2,3-d:6,5-d′]Dipyrimidines Catalyzed by a Mesoporous Recoverable Silica-Based Nanomaterial
Alireza Kohzadian
Abdolkarim Zare
Silicon, 2020, 12 : 1407 - 1415
[28] Effective and Rapid Synthesis of Pyrido[2,3-d:6,5-d′]Dipyrimidines Catalyzed by a Mesoporous Recoverable Silica-Based Nanomaterial
Kohzadian, Alireza
Zare, Abdolkarim
SILICON, 2020, 12 (06) : 1407 - 1415
[29] Sonochemical synthesis of pyrido[2,3-d:6,5-d′]-dipyrimidines catalyzed by [HNMP]+[HSO4]- and their antimicrobial activity studies
Naeimi, Hossein
Didar, Asieh
Rashid, Zahra
Zahraie, Zohreh
JOURNAL OF ANTIBIOTICS, 2017, 70 (07): : 845 - 852
[30] Sonochemical synthesis of pyrido[2,3-d:6,5-d′]-dipyrimidines catalyzed by [HNMP]+[HSO4]− and their antimicrobial activity studies
Hossein Naeimi
Asieh Didar
Zahra Rashid
Zohreh Zahraie
The Journal of Antibiotics, 2017, 70 : 845 - 852

← 1 2 3 4 5 →