An Efficient Synthesis of Pyrido[2,3-d][6,5-d]dipyrimidine and 5,5′-Arylmethylenebis(2,6-diaminopyrimidinone) Derivatives under Microwave Irradiation

被引：4

作者：

Lin, Zhilan ^{[1
]}

Hu, Huiling ^{[1
]}

You, Xinkui ^{[1
]}

Zhang, Xueli ^{[1
]}

Gao, Yuan ^{[1
]}

机构：

[1] Shenzhen Univ, Coll Chem & Chem Engn, Shenzhen 518060, Guangdong, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷 / 01期

基金：

中国国家自然科学基金;

关键词：

DIHYDROFOLATE REDUCTASES; PNEUMOCYSTIS-CARINII; TOXOPLASMA-GONDII; CRYSTAL-STRUCTURE; ANTITUMOR AGENTS; INHIBITORS; PYRIMIDINES; CHEMISTRY; ANALOGS; HEPT;

D O I：

10.1002/jhet.1647

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrido[2,3-d][6,5-d]dipyrimidine and 5,5-arylmethylenebis(2,6-diaminopyrimidinone) derivatives have been synthesized through a rapid reaction of aromatic aldehydes with aminopyrimidines in acetic acid under microwave irradiation. This method has the advantages of simple operation, high yields, short reaction time, and easy work-up.

引用

页码：277 / 281

页数：5

共 50 条

[31] ACCESS TO PYRIDAZINO[4,5-B]QUINOLINE AND PYRIDO[2,3-D - 6,5-D]DIPYRIDAZINE SERIES
GODARD, A
QUEGUINE.G
PASTOUR, P
BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE, 1971, (03): : 906 - &
[32] An efficient synthesis of pyrido[2,3-d]pyrimidine derivatives and related compounds under ultrasound irradiation without catalyst
Tu, Shujiang
Cao, Longji
Zhang, Yan
Shao, Qingqing
Zhou, Dianxiang
Li, Chunmei
ULTRASONICS SONOCHEMISTRY, 2008, 15 (03) : 217 - 221
[33] Pyrimidinethione as a building block in heterocyclic synthesis: synthesis of pyrano[2,3-d]pyrimidine, chromeno[2,3-d]pyrimidine, pyrido[3′,2′:5,6]pyrano[2,3-b]pyridine, and pyrimido[5′,4′:5,6]pyrano[2,3-d]pyrimidine derivatives
Reheim, Mohamed Ahmed Mahmoud Abdel
Hafiz, Ibrahim Saad Abdel
Elian, Mohamed Ahmed
HETEROCYCLIC COMMUNICATIONS, 2016, 22 (06) : 311 - 317
[34] An Efficient Synthesis of Pyrido[2,3-d]pyrimidine Derivatives in Ionic Liquid
Shi, Da-Qing
Zhou, Yao
Liu, Hai
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 47 (01) : 131 - 135
[35] Immobilization of Cu(II) on MWCNTs@L-His as a new high efficient reusable catalyst for the synthesis of pyrido[2,3-d:5,6-d′]dipyrimidine derivatives
Saeidiroshan, Hakimeh
Moradi, Leila
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2019, 893 : 1 - 10
[36] A greener approach for the synthesis of pyrido[2,3-d]pyrimidine derivatives in glycerol under microwave heating
Martinho, Luan A.
Andrade, Carlos Kleber Z.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 59 (08) : 1417 - 1429
[37] PYRIDO[2,3-D]PYRIMIDINES .8. SYNTHESIS OF PYRROLO(2',3'/4,5)PYRIDO[2,3-D]PIRIMIDINES
BISTRYAKOVA, ID
SMIRNOVA, NM
SAFONOVA, TS
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (06): : 800 - 803
[38] NOVEL SYNTHESIS OF 5-OXO-PYRIDO[2,3-D]PYRIMIDINES AND 7-OXO-PYRIDO[2,3-D]PYRIMIDINES
OGURA, H
SAKAGUCH.M
CHEMISTRY LETTERS, 1972, (08) : 657 - +
[39] Synthesis and antibacterial activities of 1,2,3,4,6,7,8,9,10-nonahydro-1,3,7,9,10-pentaphenyl-5-(2-furanyl)-2,8-dithio-4,6-dioxo-5H-Pyrido [2,3-d; 6,5-d′] dipyrimidine
Kumar, RN
Suresh, T
Mohan, PS
ASIAN JOURNAL OF CHEMISTRY, 2003, 15 (03) : 1447 - 1451
[40] A facile synthesis of pyrano[2,3-d:6,5-d′]dipyrimidines via microwave-assisted multicomponent reactions catalyzed by β-cyclodextrin
Avvadukkam, Jayashree
Badiadka, Narayana
Kunhanna, Sarojini B.
Kumar, Madan S.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021, 58 (03) : 724 - 736

← 1 2 3 4 5 →