An efficient chemoselective synthesis of pyrido[2,3-d]pyrimidine derivatives under microwave irradiation

被引:31
|
作者
Tu, Shujiang [1 ]
Li, Chunmei [1 ]
Shi, Feng [1 ]
Zhou, Dianxiang [1 ]
Shao, Qingqing [1 ]
Cao, Longji [1 ]
Jiang, Bo [1 ]
机构
[1] Xuzhou Normal Univ, Sch Chem & Chem Engn, Key Lab Biotechnol Med Plant, Xuzhou 221116, Jiangsu, Peoples R China
来源
SYNTHESIS-STUTTGART | 2008年 / 03期
关键词
solvent-dependent chemoselectivity; pyrido[2,3-d]pyrimidines; microwave irradiation; heterocycles; multicomponent reaction;
D O I
10.1055/s-2008-1032031
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile and selective synthesis of poly-substituted pyrido [2,3-d]pyrimidines is accomplished via microwave-assisted multicomponent reactions controlled by the nature of solvent. In addition, a possible mechanism accounting for the reaction is proposed.
引用
收藏
页码:369 / 376
页数:8
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