Total synthesis of (+)-camptothecin via an intramolecular palladium-catalyzed cyclization strategy

被引:22
|
作者
Chavan, Subhash P. [1 ]
Pathak, Ashok B. [1 ]
Kalkote, Uttam R. [1 ]
机构
[1] Natl Chem Lab, Div Organ Chem Technol, Pune 411008, Maharashtra, India
关键词
natural products; alkaloids; antitumor; palladium; cyclizations;
D O I
10.1055/s-2007-991054
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The novel cascade intramolecular Pd-catalyzed cyclization followed by aromatization for the construction Of D ring of (+)-camptothecin as a key step is demonstrated.
引用
收藏
页码:2635 / 2638
页数:4
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