A Total Synthesis of (±)-Ceratopicanol via Palladium Catalyzed Reductive Cyclization

被引：0

作者：

Kim, Rira ^{[1
]}

Lee, Sanghyeon ^{[1
]}

Lee, Jaeyeon ^{[1
]}

Lee, Hee-Yoon ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem, Daejeon 34141, South Korea

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 2020卷 / 31期

关键词：

Triquinane; Cyclization; Free radicals; Pd catalysis; Total synthesis; ENANTIOSELECTIVE TOTAL-SYNTHESIS; REARRANGEMENT;

D O I：

10.1002/ejoc.202000769

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient total synthesis of ceratopicanol was achieved through successive Pd catalyzed reductive cycloaddition and cyclization reactions. The Pd mediated cyclization reaction to form a triquinane structure demonstrated that a small structural difference changed the reaction pathway either to form different structures or reduced non-cyclized product depending on the reaction conditions.

引用

页码：4931 / 4936

页数：6

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