A facile synthesis of indolo[3,2,1-jk]carbazoles via palladium-catalyzed intramolecular cyclization

被引：39
|
作者：
Lv, Jun [1 ]
Liu, Qiancai [1 ]
Tang, Jie [1 ]
Perdih, Franc [2 ]
Kranjc, Kristof [2 ]
机构：
[1] E China Normal Univ, Dept Chem, Shanghai 200241, Peoples R China
[2] Univ Ljubljana, Fac Chem & Chem Engn, SI-1000 Ljubljana, Slovenia
来源：
TETRAHEDRON LETTERS | 2012年 / 53卷 / 39期
关键词：
Indolo[3,2,1-jk]carbazoles; Intramolecular cyclization; Palladium; Catalysis; ARYLATION;
D O I：
10.1016/j.tetlet.2012.07.093
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new efficient synthesis of indolo[3,2,1-jk]carbazoles by the palladium-catalyzed cyclization of N-(2-bromoaryl)carbazoles is described. The reaction involves intramolecular C-C bond formation, coupled with the cleavage of a C-X bond and a C-H bond on carbazole ring. Substitutions on N-aryl core with either electron-donating or electron-withdrawing groups are introduced, and different reaction factors for cyclization are evaluated. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5248 / 5252
页数：5
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