3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors

被引：0

作者：

Pokhvisneva, G. V. ^{[1
]}

Gordeev, P. B. ^{[1
]}

Nikitin, S. V. ^{[1
]}

Smirnov, G. A. ^{[1
]}

Ternikova, T. V. ^{[1
]}

Luk'yanov, O. A. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2018年 / 67卷 / 09期

基金：

俄罗斯科学基金会;

关键词：

NO donors; 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides); 2-bromoethyl derivatives; 2-hydroxyethyl derivatives; 2-nitroxyethyl derivatives; alkylation; nitration; nucleophilic substitution; NITROGEN-OXYGEN SYSTEMS; METHYLENE-BIS(1-OXY-3,3-DIALKYL-1-TRIAZENE 2-OXIDES);

D O I：

10.1007/s11172-018-2273-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3,3-Bis(2-nitroxyethyl) derivatives of 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) were synthesized by either nucleophilic substitution of the bromine atoms of parent 3,3-bis(2- bromoethyl) compounds or nitration of structurally related 3,3-bis(2-hydroxyethyl) derivatives. The synthesized compounds comprise two different NO donating moieties, namely, oxytriaz- 1-ene 2-oxide and nitrate groups, and, therefore, can be regarded as a new type of NO-donating agents.

引用

页码：1655 / 1661

页数：7

共 50 条

[1] 3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors
G. V. Pokhvisneva
P. B. Gordeev
S. V. Nikitin
G. A. Smirnov
T. V. Ternikova
O. A. Luk’yanov
Russian Chemical Bulletin, 2018, 67 : 1655 - 1661
[2] N--Nitroxyethyl derivatives of 1,1'-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)
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[3] N-β-Nitroxyethyl derivatives of 1,1’-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)
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[4] Bis-, tris-, and tetrakis-N-(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)
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[6] Synthesis of 3,3-bis(2-haloethyl) and 3,3,3′-tris(2-haloethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)
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[7] Synthesis of 3,3-bis(2-hydroxyethyl) and 3,3,3’-tris(2-hydroxyethyl) derivatives of 1,1’-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)
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[10] Synthesis of 1,1'-[methylenebis(oxy)]-bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides]
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