3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors

被引：0
|
作者：
Pokhvisneva, G. V. [1 ]
Gordeev, P. B. [1 ]
Nikitin, S. V. [1 ]
Smirnov, G. A. [1 ]
Ternikova, T. V. [1 ]
Luk'yanov, O. A. [1 ]
机构：
[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2018年 / 67卷 / 09期
基金：
俄罗斯科学基金会;
关键词：
NO donors; 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides); 2-bromoethyl derivatives; 2-hydroxyethyl derivatives; 2-nitroxyethyl derivatives; alkylation; nitration; nucleophilic substitution; NITROGEN-OXYGEN SYSTEMS; METHYLENE-BIS(1-OXY-3,3-DIALKYL-1-TRIAZENE 2-OXIDES);
D O I：
10.1007/s11172-018-2273-6
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
3,3-Bis(2-nitroxyethyl) derivatives of 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) were synthesized by either nucleophilic substitution of the bromine atoms of parent 3,3-bis(2- bromoethyl) compounds or nitration of structurally related 3,3-bis(2-hydroxyethyl) derivatives. The synthesized compounds comprise two different NO donating moieties, namely, oxytriaz- 1-ene 2-oxide and nitrate groups, and, therefore, can be regarded as a new type of NO-donating agents.
引用
收藏
页码：1655 / 1661
页数：7
相关论文
共 50 条
  • [31] Bis[μ-1,1′-methylenebis(1H-imidazole)-κ2 N3:N3′]bis[dichloridocobalt(II)]
    Feng, Miao
    Mi, Huai-Feng
    Hu, Tong-Liang
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : M491 - U947
  • [32] Preparation of 1,1'-Oxy-bis(3,3-bis(trifluoromethyl)-3(1H)-1,2-benziodoxole) and 2-(N-(p-Toluenesulfonyl)imino)iodobenzylmethyl Ether
    Blake, Alexander J.
    Novak, Andrew
    Davies, Madeline
    Robinson, Richard I.
    Woodward, Simon
    SYNTHETIC COMMUNICATIONS, 2009, 39 (06) : 1065 - 1075
  • [33] Synthesis of 1-alkoxy-3-methyl-1-triazene 2-oxides and 3, 3´-methylene-bis(1-alkoxy-3-methyl-1-triazene 2-oxides)
    G. A. Smirnov
    P. B. Gordeev
    S. V. Nikitin
    G. V. Pokhvisneva
    T. V. Ternikova
    O. A. Luk’yanov
    Russian Chemical Bulletin, 2015, 64 : 2712 - 2717
  • [34] (S)-2,2′-bis(methoxymethoxy)[1,1′-binaphthyl]-3,3′- dicarbaldehyde
    Tachi, Y
    Nakayama, S
    Tani, F
    Ueno, G
    Naruta, Y
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1999, 55 : 1351 - 1353
  • [35] 1,3-bis(pyrrolidin-2-on-1-yl)but-1-ene
    Zhuo, JC
    MOLECULES, 1999, 4 (11) : M117 - M117
  • [36] 1,3-Bis[(3-chloropyrazin-2-yl)oxy]benzene
    Srinivasan, Thothadri
    Kalpana, Venkatesan
    Rajakumar, Perumal
    Velmurugan, Devadasan
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O815 - +
  • [37] [3,3′-Bis(1-naphthylmethyl)-1,1′-(2,2′-oxydiethylene)bis(imidazol-2-ylidene)]mercury(II) bis(hexafluoridophosphate) acetonitrile solvate
    Guo, Wen-Yan
    Dong, Gui-Ying
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : M217 - U897
  • [38] 1,3,2-DIAZAPHOSPHORINE 2-OXIDES .3. PREPARATION AND BIOLOGICAL EVALUATION OF SOME 1,3-BIS(ARALKYL)-2-HALO-1,3,2-DIAZAPHOSPHORINE 2-OXIDES AND RELATED COMPOUNDS
    BILLMAN, JH
    MEISENHEIMER, JL
    MAY, RF
    JOURNAL OF MEDICINAL CHEMISTRY, 1966, 9 (05) : 772 - +
  • [39] 1,1′-{2,2′-[1,4-Phenylenebis(methylene)]bis(oxy)bis(2,1-phenylene)}diethanone
    Al-Mohammed, Nassir N. N.
    Alias, Yatimah
    Abdullah, Zanariah
    Khaledi, Hamid
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O3016 - U1230
  • [40] 2,2′-Bis(methoxymethoxy)-3,3′-diphenyl-1,1′-binaphthalene
    Zong, Hua
    Huang, Hua-Yin
    Hu, Bing
    Bian, Guang-Ling
    Song, Ling
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O222 - U3316
12345