3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors

被引:0
|
作者
Pokhvisneva, G. V. [1 ]
Gordeev, P. B. [1 ]
Nikitin, S. V. [1 ]
Smirnov, G. A. [1 ]
Ternikova, T. V. [1 ]
Luk'yanov, O. A. [1 ]
机构
[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia
基金
俄罗斯科学基金会;
关键词
NO donors; 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides); 2-bromoethyl derivatives; 2-hydroxyethyl derivatives; 2-nitroxyethyl derivatives; alkylation; nitration; nucleophilic substitution; NITROGEN-OXYGEN SYSTEMS; METHYLENE-BIS(1-OXY-3,3-DIALKYL-1-TRIAZENE 2-OXIDES);
D O I
10.1007/s11172-018-2273-6
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
3,3-Bis(2-nitroxyethyl) derivatives of 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) were synthesized by either nucleophilic substitution of the bromine atoms of parent 3,3-bis(2- bromoethyl) compounds or nitration of structurally related 3,3-bis(2-hydroxyethyl) derivatives. The synthesized compounds comprise two different NO donating moieties, namely, oxytriaz- 1-ene 2-oxide and nitrate groups, and, therefore, can be regarded as a new type of NO-donating agents.
引用
收藏
页码:1655 / 1661
页数:7
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