3,3-Bis(2-nitroxyethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) as a new type of NO donors

被引：0

作者：

Pokhvisneva, G. V. ^{[1
]}

Gordeev, P. B. ^{[1
]}

Nikitin, S. V. ^{[1
]}

Smirnov, G. A. ^{[1
]}

Ternikova, T. V. ^{[1
]}

Luk'yanov, O. A. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2018年 / 67卷 / 09期

基金：

俄罗斯科学基金会;

关键词：

NO donors; 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides); 2-bromoethyl derivatives; 2-hydroxyethyl derivatives; 2-nitroxyethyl derivatives; alkylation; nitration; nucleophilic substitution; NITROGEN-OXYGEN SYSTEMS; METHYLENE-BIS(1-OXY-3,3-DIALKYL-1-TRIAZENE 2-OXIDES);

D O I：

10.1007/s11172-018-2273-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3,3-Bis(2-nitroxyethyl) derivatives of 1,1 '-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) were synthesized by either nucleophilic substitution of the bromine atoms of parent 3,3-bis(2- bromoethyl) compounds or nitration of structurally related 3,3-bis(2-hydroxyethyl) derivatives. The synthesized compounds comprise two different NO donating moieties, namely, oxytriaz- 1-ene 2-oxide and nitrate groups, and, therefore, can be regarded as a new type of NO-donating agents.

引用

页码：1655 / 1661

页数：7

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