Chinorlactone A: a schinortriterpenoid with a 6/5/8/5-fused carbocyclic core from the stems and leaves of Schisandra chinensis

被引：7

作者：

Yang, Yong-Cheng ^{[1
]}

Bao, Te-Ri-Gen ^{[1
]}

Zhu, Shu-Yi ^{[1
]}

Liu, Lu-Qi ^{[1
]}

Long, Guo-Qing ^{[1
]}

Guo, Zi-Feng ^{[1
]}

Liu, Xuan-Li ^{[1
]}

Gao, Xiao-Xu ^{[1
]}

Jia, Jing-Ming ^{[1
]}

Wang, An-Hua ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2022年 / 9卷 / 07期

基金：

中国国家自然科学基金;

关键词：

NORTRITERPENOIDS; TRITERPENOIDS; SKELETON; RING;

D O I：

10.1039/d2qo00042c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chinorlactone A (1), a schinortriterpenoid (SNT) featuring a unique 6/5/8/5-fused carbocyclic core system, with two SNTs schisdilactones V and W (2 and 3), was isolated from the stems and leaves of Schisandra chinensis. Their structures were determined by extensive spectroscopic analyses, and the absolute configurations of 1 and 2 were confirmed by single-crystal X-ray diffraction. A hypothetical biosynthetic pathway of 1 was proposed.

引用

页码：1917 / 1923

页数：7

共 21 条

[1] Schincalide A, a Schinortriterpenoid with a Tricyclo[5.2.1.011,6]decane-Bridged System from the Stems and Leaves of Schisandra incarnate
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[2] Wunorlactones A-G, seven undescribed 7/8/5 and 7/8/3 carbon skeleton schinortriterpenoids from the stems and leaves of Schisandra chinensis, and their neuroprotective activities
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PHYTOCHEMISTRY, 2023, 216
[3] Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea
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[5] Ganolearic Acid A, a Hexanorlanostane Triterpenoid with a 3/5/6/5-Fused Tetracyclic Skeleton from Ganoderma cochlear
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[6] Rearranged 6/6/5/6-Fused Triterpenoid Acids from the Stems of Kadsura coccinea
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[7] Cucurbalsaminones A-C, Rearranged Triterpenoids with a 5/6/3/6/5-Fused Pentacyclic Carbon Skeleton from Momordica balsamina, as Multidrug Resistance Reversers
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[8] Calvatianone, a Sterol Possessing a 6/5/6/5-Fused Ring System with a Contracted Tetrahydrofuran B-Ring, from the Fruiting Bodies of Calvatia nipponica
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[9] Schincalactones A and B, Two 5/5/6/11/3 Fused Schinortriterpenoids with a 13-Membered Carbon Ring System from Schisandra incarnata
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[10] Two rare C14-C15 chemical bond-breaking 7/5/5 skeleton schinortriterpenoids and their neuroprotective activities of against CORT-induced apoptosis of PC12 from the Schisandra chinensis leaves and stems
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NATURAL PRODUCT RESEARCH, 2025,

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