Urinary metabolites of daidzin orally administered in rats

被引：0

作者：

Yasuda, T ^{[1
]}

Ohsawa, K ^{[1
]}

机构：

[1] Tohoku Coll Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9818558, Japan

来源：

BIOLOGICAL & PHARMACEUTICAL BULLETIN | 1998年 / 21卷 / 09期

关键词：

daidzin; Puerariae lobata OHWI; urinary metabolite; 3; 4; 7-trihydroxyisoflavone; 7-dihydroxyisoflavanone; equol;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In a study on the metabolism of flavonoids, the isoflavone glycoside daidzin was orally administered to rats. Urine samples were collected and treated,with beta-glucuronidase and arylsulfatase. Aglycone daidzein (M3) and other three metabolites, 3',4',7-trihydroxyisoflavone (M1), 4',7-dihydroxyisoflavanone (M2) and 4',7-dihydroxyisoflavan (M4) were isolated from the urine following treatment with enzymes. The structures of M1, M2 and M4 were determined on the basis of chemical and spectral data.

引用

页码：953 / 957

页数：5

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