Urinary metabolites of daidzin orally administered in rats

被引：0
|
作者：
Yasuda, T [1 ]
Ohsawa, K [1 ]
机构：
[1] Tohoku Coll Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9818558, Japan
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 1998年 / 21卷 / 09期
关键词：
daidzin; Puerariae lobata OHWI; urinary metabolite; 3; 4; 7-trihydroxyisoflavone; 7-dihydroxyisoflavanone; equol;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In a study on the metabolism of flavonoids, the isoflavone glycoside daidzin was orally administered to rats. Urine samples were collected and treated,with beta-glucuronidase and arylsulfatase. Aglycone daidzein (M3) and other three metabolites, 3',4',7-trihydroxyisoflavone (M1), 4',7-dihydroxyisoflavanone (M2) and 4',7-dihydroxyisoflavan (M4) were isolated from the urine following treatment with enzymes. The structures of M1, M2 and M4 were determined on the basis of chemical and spectral data.
引用
收藏
页码：953 / 957
页数：5
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