Urinary metabolites of daidzin orally administered in rats

被引：0
|
作者：
Yasuda, T [1 ]
Ohsawa, K [1 ]
机构：
[1] Tohoku Coll Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9818558, Japan
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 1998年 / 21卷 / 09期
关键词：
daidzin; Puerariae lobata OHWI; urinary metabolite; 3; 4; 7-trihydroxyisoflavone; 7-dihydroxyisoflavanone; equol;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In a study on the metabolism of flavonoids, the isoflavone glycoside daidzin was orally administered to rats. Urine samples were collected and treated,with beta-glucuronidase and arylsulfatase. Aglycone daidzein (M3) and other three metabolites, 3',4',7-trihydroxyisoflavone (M1), 4',7-dihydroxyisoflavanone (M2) and 4',7-dihydroxyisoflavan (M4) were isolated from the urine following treatment with enzymes. The structures of M1, M2 and M4 were determined on the basis of chemical and spectral data.
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收藏
页码：953 / 957
页数：5
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