Synthesis and Antimicrobial Screening of Some Novel Pyrazoline Derivatives

被引：0

作者：

Kundariya, D. S. ^{[1
]}

Rupala, R. G. ^{[1
]}

Patel, P. K. ^{[1
]}

机构：

[1] Maharaja Shree Mahendrasinhji Sci Coll, Dept Chem, Morbi 363642, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2012年 / 24卷 / 05期

关键词：

Chalcones; Pyrazolines; Antimicrobial activity; ANTIBACTERIAL;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of methyl-4-(4,5-dihydro-5-[(Z)phenyl]-1H-pyrazol-3-yl)-2-methylbenzohydrazide were synthesized by cyclisization of chalcones, methyl 4-((E)-3-((Z)phenyl)acryloyl)-2-methylbenzoate with hydrazine hydrate in presence of basic media. The chalcones were synthesized starting from 4-acetyl-2-methylbenzoic acid in 2 step. The structures of the synthesized compounds have been established on the basis of physical and spectral data and are screened for antimicrobial activity. Some of them exhibited significant activity.

引用

页码：2045 / 2048

页数：4

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