On the Hardness of Counting and Sampling Center Strings

被引:0
|
作者
Boucher, Christina [1 ]
Omar, Mohamed [2 ]
机构
[1] Univ Waterloo, David R Cheriton Sch Comp Sci, Waterloo, ON N2L 3G1, Canada
[2] Univ Calif, Dept Math, Davis, CA USA
关键词
PRIMERS; DESIGN; GRAPHS; ALGORITHMS; PROGRAM;
D O I
暂无
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Given a set S of n strings, each of length P, and a non-negative value d, we define a center string as a string of length E that has Hamming distance at most d from each string in S. The #CLOSEST STRING problem aims to determine the number of unique center strings for a given set of strings S and input parameters n, l, and d. We show #CLOSEST STRING is impossible to solve exactly or even approximately in polynomial time, and that restricting #CLOSEST STRING so that any one of the parameters n, l, or d is fixed leads to an FPRAS. We show equivalent results for the problem of efficiently sampling center strings uniformly at random.
引用
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页码:127 / +
页数:3
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