Diagnostic Performance of Dynamic Myocardial Perfusion Imaging Using Dual-Source Computed Tomography

被引：27

作者：

Kitagawa, Kakuya ^{[1
]}

Nakamura, Satoshi ^{[2
]}

Ota, Hideki ^{[3
]}

Ogawa, Ryo ^{[4
]}

Shizuka, Takehito ^{[5
]}

Kubo, Tadahiro ^{[6
]}

Yi, Yan ^{[7
]}

Ito, Tatsuro ^{[8
]}

Nagasawa, Naoki ^{[2
]}

Omori, Taku ^{[9
]}

Nakamori, Shiro ^{[9
]}

Kurita, Tairo ^{[10
]}

Sugisawa, Jun ^{[10
]}

Hatori, Naoki ^{[5
]}

Nakashima, Hitoshi ^{[6
]}

Wang, Yining ^{[7
]}

Kido, Teruhito ^{[4
]}

Watanabe, Kouki ^{[11
]}

Matsumoto, Yasuharu ^{[10
,12
]}

Dohi, Kaoru ^{[9
]}

Sakuma, Hajime ^{[13
]}

机构：

[1] Mie Univ, Grad Sch Med, Dept Adv Diagnost Imaging, 2-174 Edobashi, Tsu, Mie 5148507, Japan

[2] Mie Univ Hosp, Dept Radiol, Tsu, Mie, Japan

[3] Tohoku Univ Hosp, Dept Diagnost Radiol, Sendai, Miyagi, Japan

[4] Ehime Univ, Dept Radiol, Grad Sch Med, Matsuyama, Ehime, Japan

[5] Natl Hosp Org, Takasaki Gen Med Ctr, Dept Cardiol, Takasaki, Gumma, Japan

[6] Natl Hosp Org, Kagoshima Med Ctr, Dept Cardiovasc Med, Kagoshima, Japan

[7] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Radiol, Beijing, Peoples R China

[8] Kobe Univ, Grad Sch Med, Dept Cardiovasc Med, Kobe, Hyogo, Japan

[9] Mie Univ, Dept Cardiol & Nephrol, Grad Sch Med, Tsu, Mie, Japan

[10] Tohoku Univ, Dept Cardiovasc Med, Sch Med, Sendai, Miyagi, Japan

[11] Saiseikai Matsuyama Hosp, Div Cardiol, Matsuyama, Ehime, Japan

[12] Int Univ Hlth & Welf, Shioya Hosp, Dept Cardiovasc Med, Yaita, Japan

[13] Mie Univ, Dept Radiol, Grad Sch Med, Tsu, Mie, Japan

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2021年 / 78卷 / 20期

关键词：

4-dimensional computed tomography; coronary artery disease; multicenter study; myocardial ischemia; myocardial perfusion imaging; FRACTIONAL FLOW RESERVE; CORONARY-ARTERY-DISEASE; BLOOD-FLOW; PROGNOSTIC VALUE; MEDICAL THERAPY; STENOSIS; CT; ANGIOGRAPHY; REVASCULARIZATION; ACCURACY;

D O I：

10.1016/j.jacc.2021.08.067

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

RESULTS The study protocol was completed in 157 participants, and hemodynamically significant stenosis was detected in 76 of 157 patients (48%) and 112 of 442 vessels (25%). According to receiver-operating characteristic curve analysis, adding dynamic CTP to CTA significantly increased the area under the curve from 0.65 (95% CI: 0.57-0.72) to 0.74 (95% CI: 0.66-0.81; P 1/4 0.011) on the patient level, with decreased sensitivity (93% vs 72%; P < 0.001), improved specificity (36% vs 75%; P < 0.001), and improved overall accuracy (64% vs 74%; P < 0.001).

引用

页码：1937 / 1949

页数：13

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