Synthesis of chromene-2-thiones and in vitro evaluation of their antifungal and antibacterial activities

被引：0

作者：

Devi, Nepram Sushuma ^{[1
]}

Singh, Thokchom Prasanta ^{[1
]}

Khumanthem, Nonibala ^{[2
]}

Singh, Okram Mukherjee ^{[1
]}

机构：

[1] Manipur Univ, Dept Chem, Imphal 795003, Manipur, India

[2] Manipur Univ, Dept Life Sci, Imphal 795003, Manipur, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2013年 / 52卷 / 09期

关键词：

beta-Oxodithioester; cupric chloride; coumarin; solvent free; antimicrobial activity; COUMARIN DERIVATIVES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclocondensation of beta-oxodithioesters with substituted 2-hydroxy benzaldehydes in presence of copper(II)chloride as the catalyst yields 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones (87-95% yields). These reactions are carried out under solvent-free conditions. All the synthesized compounds have been evaluated for their antifungal and antibacterial activities using tube dilution technique. Only five compounds are found exhibiting good antifungal and antibacterial activities.

引用

页码：1224 / 1231

页数：8

共 50 条

[41] In Vitro Antifungal and Antibacterial Activities of Pentacycloundecane Tetra-Amines
Onajole, Oluseye K.
Coovadia, Yacoob
Govender, Thavendran
Kruger, Hendrik G.
Maguire, Glenn E. M.
Naidu, Dianithi
Singh, Nisha
Govender, Patrick
CHEMICAL BIOLOGY & DRUG DESIGN, 2011, 77 (04) : 295 - 299
[42] Synthesis of some benzimidazole derivatives and their antibacterial and antifungal activities
Küçükbay, H
Durmaz, R
Güven, M
Günal, S
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 2001, 51 (05): : 420 - 424
[43] Synthesis of some heterocyclic phosphonates and their antibacterial and antifungal activities
Mete, A
Sener, S
Kücükbay, H
Günal, S
Durmaz, R
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1999, 38 (02): : 197 - 200
[44] Synthesis, Antibacterial, and Antifungal Activities of Novel Pyridazino Carbazoles
Yaqub, Ghazala
Hannan, Abdul
Akbar, Erum
Usman, Muhammad
Hamid, Almas
Sadiq, Zubi
Iqbal, Mehwish
JOURNAL OF CHEMISTRY, 2013, 2013
[45] Synthesis of Some Benzimidazole Derivatives and Their Antibacterial and Antifungal Activities
Kucukbay, Hasan
Durmazt, Riza
Sirecitt, Nihat
Gunalt, Selami
ASIAN JOURNAL OF CHEMISTRY, 2009, 21 (08) : 6181 - 6189
[46] SYNTHESIS OF PYRAZOLE DERIVATIVES AND SCREENING OF THEIR ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES
Mistry, B. D.
Desai, K. R.
Intwala, S. M.
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 23 (02) : 201 - 206
[47] Thermal solvent-free synthesis of chromonyl chalcones, pyrazolines and their in vitro antibacterial, antifungal activities
Siddiqui, Zeba N.
Praveen, Shagufta
Musthafa, Mohammed T. N.
Ahmad, Anis
Khan, Asad U.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2012, 27 (01) : 84 - 91
[48] Enantioselective synthesis of 2-amino-4H-chromene derivatives with antifungal activities on phytopathogenic fungi
Zhang, Man
Ru, Yifan
Wang, Shilin
Fu, Wen
Li, Tianyu
Shao, Xusheng
Li, Zhong
Yang, Wu-Lin
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (13): : 3692 - 3699
[49] Synthesis and Evaluation of Antibacterial and Antifungal Activities of 1,3-Disubstituted-4-thioxoimidazolidin-2-one Derivatives
EL-Sharief, Marwa A. M. Sh
Abbas, Samir Y.
Moussa, Ziad
EL-Gammal, Eman W.
EL-Sharief, Ahmed M. Sh
CROATICA CHEMICA ACTA, 2018, 91 (03) : 335 - 340
[50] Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities
Wang, Xian-Long
Wan, Kun
Zhou, Cheng-He
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (10) : 4631 - 4639

← 1 2 3 4 5 →