Synthesis of chromene-2-thiones and in vitro evaluation of their antifungal and antibacterial activities

被引：0

作者：

Devi, Nepram Sushuma ^{[1
]}

Singh, Thokchom Prasanta ^{[1
]}

Khumanthem, Nonibala ^{[2
]}

Singh, Okram Mukherjee ^{[1
]}

机构：

[1] Manipur Univ, Dept Chem, Imphal 795003, Manipur, India

[2] Manipur Univ, Dept Life Sci, Imphal 795003, Manipur, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2013年 / 52卷 / 09期

关键词：

beta-Oxodithioester; cupric chloride; coumarin; solvent free; antimicrobial activity; COUMARIN DERIVATIVES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclocondensation of beta-oxodithioesters with substituted 2-hydroxy benzaldehydes in presence of copper(II)chloride as the catalyst yields 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones (87-95% yields). These reactions are carried out under solvent-free conditions. All the synthesized compounds have been evaluated for their antifungal and antibacterial activities using tube dilution technique. Only five compounds are found exhibiting good antifungal and antibacterial activities.

引用

页码：1224 / 1231

页数：8

共 50 条

[11] Design, synthesis and in vitro evaluation of the antibacterial and antifungal activity of some new dihydropyrano[3,2-c] chromene derivatives
Shah, Amish I.
Raj, Dilipsinh S.
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2012, 2 (03): : 320 - 331
[12] Synthesis of benzimidazolylphenothiazines and their antibacterial and antifungal activities
Bhatt, AK
Karadia, HG
Shah, PR
Parmar, MP
Patel, HD
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 13 (03) : 281 - 282
[13] In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
Bhat, Showkat Ahmad
Zargar, Mohammed Iqbal
Wani, Shahid Ud Din
Mohiuddin, Ishfaq
Masoodi, Mubashir Hussain
Shakeel, Faiyaz
Ali, Mohammad
Mehdi, Seema
JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES, 2024, 10 (01)
[14] In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
Showkat Ahmad Bhat
Mohammed Iqbal Zargar
Shahid Ud Din Wani
Ishfaq Mohiuddin
Mubashir Hussain Masoodi
Faiyaz Shakeel
Mohammad Ali
Seema Mehdi
Journal of Pharmaceutical Health Care and Sciences, 10
[15] Synthesis and in vitro evaluation of antifungal and cytotoxic activities of eugenol glycosides
Thiago Belarmino de Souza
Marina Orlandi
Luiz Felipe Leomil Coelho
Luiz Cosme Cotta Malaquias
Amanda Latercia Tranches Dias
Roberta Ribeiro de Carvalho
Naiara Chaves Silva
Diogo Teixeira Carvalho
Medicinal Chemistry Research, 2014, 23 : 496 - 502
[16] Synthesis and in vitro evaluation of antifungal and cytotoxic activities of eugenol glycosides
de Souza, Thiago Belarmino
Orlandi, Marina
Leomil Coelho, Luiz Felipe
Cotta Malaquias, Luiz Cosme
Tranches Dias, Amanda Latercia
de Carvalho, Roberta Ribeiro
Silva, Naiara Chaves
Carvalho, Diogo Teixeira
MEDICINAL CHEMISTRY RESEARCH, 2014, 23 (01) : 496 - 502
[17] Synthesis of 2,3-Bis(halomethyl)quinoxaline Derivatives and Evaluation of Their Antibacterial and Antifungal Activities
Ishikawa, Hisato
Sugiyama, Takayuki
Yokoyama, Akihiro
CHEMICAL & PHARMACEUTICAL BULLETIN, 2013, 61 (04) : 438 - 444
[18] Convenient one-pot synthesis of novel 2-substituted benzimidazoles, tetrahydrobenzimidazoles and imidazoles and evaluation of their in vitro antibacterial and antifungal activities
Sharma, Shweta
Gangal, Saloni
Rauf, Abdul
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (04) : 1751 - 1757
[19] Synthesis, Antibacterial and Antifungal Activities of Bifonazole Derivatives
El Hage, Salome
Lajoie, Barbora
Feuillolay, Catherine
Roques, Christine
Baziard, Genevieve
ARCHIV DER PHARMAZIE, 2011, 344 (06) : 402 - 410
[20] IN VITRO STUDIES ON ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF EMBLICA OFFICINALIS
Hossain, Mir Monir
Mazumder, Kishor
Hossen, S. M. Moazzem
Tanmy, Tasmuna Tamrin
Rashid, Md. Jabir
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (04): : 1124 - 1127

← 1 2 3 4 5 →