Synthesis of isoquinoline alkaloid derivatives from eugenol

被引：2
|
作者：
Mikhailovskii, A. G. [1 ]
Surikova, O. V. [1 ]
Limanskii, E. S. [1 ]
Vakhrin, M. I. [1 ]
机构：
[1] Perm State Pharmaceut Acad, Perm 614990, Russia
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2012年 / 48卷 / 02期
关键词：
eugenol; phase-transfer catalysis (18-crown-6/KOH); alkylation; nitriles; Ritter reaction; isoquinoline derivatives; imines and enamines; dioxyline and papaverine analogs;
D O I：
10.1007/s10600-012-0222-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Alkylation under phase-transfer catalysis conditions (18-crown-6/KOH) of eugenol was used for cyclocondensation with nitriles (Ritter reaction), the products of which were isoquinoline derivatives.
引用
收藏
页码：285 / 287
页数：3
相关论文
共 50 条
  • [21] SYNTHESIS OF NEW DERIVATIVES OF EUGENOL AND ISOEUGENOL
    BHAGAT, SD
    MATHUR, RK
    JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1982, 27 (02): : 209 - 210
  • [22] Application of aziridines for the synthesis of isoquinoline derivatives
    Penkova, M.
    Nikolova, S.
    BULGARIAN CHEMICAL COMMUNICATIONS, 2017, 49 : 105 - 111
  • [23] SYNTHESIS AND REACTIONS OF SOME ISOQUINOLINE DERIVATIVES
    ELKHAWAGA, AM
    ELNAGGAR, GM
    HASSAN, KM
    ELDEAN, AMK
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1989, 44 (3-4): : 203 - 207
  • [24] Synthesis of tetrahydro-isoquinoline derivatives
    Decker, H
    Becker, P
    JUSTUS LIEBIGS ANNALEN DER CHEMIE, 1913, 395 (1/3): : 342 - 362
  • [25] SYNTHESIS OF TRIFLUOROMETHYL DERIVATIVES OF QUINOLINE AND ISOQUINOLINE
    Fujisaka, Aki
    Aomatsu, Daiki
    Kakutani, Yoichiro
    Terai, Ryuya
    Sakaguchi, Kumiko
    Ikejiri, Masahiro
    Miyashita, Kazuyuki
    HETEROCYCLES, 2022, 104 (03) : 572 - 583
  • [26] First total synthesis of a novel monoterpenoid isoquinoline alkaloid, (±)-alangine
    Takayama, H
    Arai, M
    Kitajima, M
    Aimi, N
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (08) : 1141 - 1143
  • [27] TOTAL SYNTHESIS OF ISOQUINOLINE ALKALOID (+1-)-XYLOPININE BY THERMOLYSIS
    KAMETANI, T
    TAKAHASHI, T
    OGASAWARA, K
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1972, (11) : 675 - +
  • [28] (±)-heterocarpine, a hydroxymethylated isoquinoline alkaloid from Ceratocapnos heterocarpa
    Suau, R
    Posadas, N
    Silva, MV
    Valpuesta, M
    PHYTOCHEMISTRY, 1998, 49 (08) : 2551 - 2555
  • [29] Coulteroberbinone, a quaternary isoquinoline alkaloid from Romneya coulteri
    Valpuesta, M
    Díaz, A
    Suau, R
    PHYTOCHEMISTRY, 1999, 51 (08) : 1157 - 1160
  • [30] Hendersine A, a novel isoquinoline alkaloid from Corydalis hendersonii
    Yin, Xu
    Bai, Ruifeng
    Guo, Qiang
    Su, Guozhu
    Wang, Jing
    Yang, Xinyao
    Li, Li
    Tu, Pengfei
    Chai, Xingyun
    TETRAHEDRON LETTERS, 2016, 57 (43) : 4858 - 4862
12345