Synthesis of isoquinoline alkaloid derivatives from eugenol

被引：2
|
作者：
Mikhailovskii, A. G. [1 ]
Surikova, O. V. [1 ]
Limanskii, E. S. [1 ]
Vakhrin, M. I. [1 ]
机构：
[1] Perm State Pharmaceut Acad, Perm 614990, Russia
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2012年 / 48卷 / 02期
关键词：
eugenol; phase-transfer catalysis (18-crown-6/KOH); alkylation; nitriles; Ritter reaction; isoquinoline derivatives; imines and enamines; dioxyline and papaverine analogs;
D O I：
10.1007/s10600-012-0222-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Alkylation under phase-transfer catalysis conditions (18-crown-6/KOH) of eugenol was used for cyclocondensation with nitriles (Ritter reaction), the products of which were isoquinoline derivatives.
引用
收藏
页码：285 / 287
页数：3
相关论文
共 50 条
  • [31] Stephaoxocanidine, a new isoquinoline alkaloid from Stephania cepharantha
    Kashiwaba, N
    Morooka, S
    Kimura, M
    Ono, M
    Toda, J
    Suzuki, H
    Sano, T
    NATURAL PRODUCT LETTERS, 1997, 9 (03): : 177 - 180
  • [32] Synthesis, Antioxidant and Antituberculosis Evaluation of Eugenol Derivatives from Mannich Condensation
    El Ghallab, Yassine
    Aainouss, Achraf
    El Messaoudi, My Driss
    Derfoufi, Sanae
    CHEMISTRYSELECT, 2024, 9 (01):
  • [33] SYNTHESIS OF ISOCOUMARIN AND ISOQUINOLINE DERIVATIVES FROM 2-ACETONYL FURAN
    GOMES, LM
    AICART, M
    COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1977, 285 (16): : 571 - 574
  • [34] Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]isoquinoline Alkaloid Derivatives
    Xu, Xin-Ming
    Zhao, Liang
    Zhu, Jieping
    Wang, Mei-Xiang
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (11) : 3799 - 3803
  • [35] PUNTARENINE - AN UNUSUAL ISOQUINOLINE ALKALOID
    FAJARDO, V
    ELANGO, V
    CHATTOPADHYAY, S
    JACKMAN, LM
    SHAMMA, M
    TETRAHEDRON LETTERS, 1983, 24 (02) : 155 - 158
  • [36] PESHAWARINE, AN UNUSUAL ISOQUINOLINE ALKALOID
    SHAMMA, M
    ROTHENBERG, AS
    JAYATILAKE, GS
    HUSSAIN, SF
    HETEROCYCLES, 1976, 5 : 41 - 45
  • [37] Mandelonitrile in Synthesis of Partially Hydrogenated Isoquinoline Derivatives
    Kharitonova, A. V.
    Gorbunov, A. A.
    Shklyaev, Yu. V.
    RUSSIAN JOURNAL OF APPLIED CHEMISTRY, 2010, 83 (08) : 1489 - 1493
  • [38] SYNTHESIS, ANTIAGGREGATORY AND ANTIHYPERTENSIVE ACTIVITY OF ISOQUINOLINE DERIVATIVES
    DORMIDONTOV, MY
    SYROPYATOV, BY
    DAUTOVA, RZ
    ALEKSANDROV, BB
    SHKLYAEV, VS
    VAKHRIN, MI
    MIKHAILOVSKY, AG
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1990, 24 (12): : 22 - 24
  • [39] Synthesis of monoterpene alkaloid derivatives from the iridoid glucoside geniposide
    Liu, Xiaohong
    Lou, Hongxiang
    NATURAL PRODUCT RESEARCH, 2007, 21 (13) : 1157 - 1164
  • [40] NEW METHOD OF SYNTHESIS OF ISOQUINOLINE AND ITS DERIVATIVES
    ZIELINSKI, W
    ROCZNIKI CHEMII, 1972, 46 (7-8): : 1455 - +
12345