Synthesis of isoquinoline alkaloid derivatives from eugenol

被引：2
|
作者：
Mikhailovskii, A. G. [1 ]
Surikova, O. V. [1 ]
Limanskii, E. S. [1 ]
Vakhrin, M. I. [1 ]
机构：
[1] Perm State Pharmaceut Acad, Perm 614990, Russia
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2012年 / 48卷 / 02期
关键词：
eugenol; phase-transfer catalysis (18-crown-6/KOH); alkylation; nitriles; Ritter reaction; isoquinoline derivatives; imines and enamines; dioxyline and papaverine analogs;
D O I：
10.1007/s10600-012-0222-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Alkylation under phase-transfer catalysis conditions (18-crown-6/KOH) of eugenol was used for cyclocondensation with nitriles (Ritter reaction), the products of which were isoquinoline derivatives.
引用
收藏
页码：285 / 287
页数：3
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