Fine and bidirectional regulation of toehold-mediated DNA strand displacement by a wedge-like DNA tool

被引：11
|
作者：
Li, Longjie [1 ,2 ]
Zhang, Wenkai [1 ,3 ]
Tang, Xiaofeng [1 ]
Li, Zejian [1 ]
Wu, Yuzhou [2 ]
Xiao, Xianjin [1 ,3 ]
机构：
[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Inst Reprod Hlth, Wuhan 430030, Peoples R China
[2] Huazhong Univ Sci & Technol, Hubei Key Lab Bioinorgan Chem & Mat Med, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China
[3] Huazhong Univ Sci & Technol, Dept Obstet & Gynaecol, Union Hosp, Tone Med Coll, Wuhan 430022, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 62期
基金：
中国国家自然科学基金;
关键词：
CIRCUITS; SWITCHES; KINETICS;
D O I：
10.1039/d0cc03722b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A wedge-like tool was established to finely and bidirectionally regulate the displacement rate of toehold-mediated strand displacement. This novel tool is very robust in terms of sequence generality and is compatible with most of the current DNA nanodevices based on traditional toehold reactions.
引用
收藏
页码：8794 / 8797
页数：4
相关论文
共 50 条
  • [41] DNA Switch: Toehold-Mediated DNA Isothermal Amplification for Dengue Serotyping
    Chan, Soo Khim
    Kuzuya, Akinori
    Choong, Yee Siew
    Lim, Theam Soon
    SLAS DISCOVERY, 2019, 24 (01) : 68 - 76
  • [42] Dynamic monitoring of an enzymatically driven dissipative toehold-mediated strand displacement reaction
    Li, Shuang
    Zhao, Disong
    Yang, Fangfang
    Liu, Shufeng
    CHEMICAL COMMUNICATIONS, 2024, 60 (05) : 570 - 573
  • [43] Cascade Toehold-Mediated Strand Displacement Reaction for Ultrasensitive Detection of Exosomal MicroRNA
    Miao, Peng
    Tang, Yuguo
    CCS CHEMISTRY, 2021, 3 (07): : 2331 - 2339
  • [44] Toehold-mediated strand displacement reaction-dependent fluorescent strategy for sensitive detection of uracil-DNA glycosylase activity
    Wu, Yushu
    Wang, Lei
    Jiang, Wei
    BIOSENSORS & BIOELECTRONICS, 2017, 89 : 984 - 988
  • [45] Recent advances in molecular machines based on toehold-mediated strand displacement reaction
    Yijun Guo
    Bing Wei
    Shiyan Xiao
    Dongbao Yao
    Hui Li
    Huaguo Xu
    Tingjie Song
    Xiang Li
    Haojun Liang
    Quantitative Biology, 2017, 5 (01) : 25 - 41
  • [46] Human Mitochondrial Helicase Twinkle Catalyzes Toehold Mediated DNA Strand Displacement
    Singh, Anupam
    Patel, Gayatri
    Johnson, Laura C.
    Patel, Smita S.
    BIOPHYSICAL JOURNAL, 2021, 120 (03) : 137A - 137A
  • [47] Toehold-Mediated Displacement of an Adenosine-Binding Aptamer from a DNA Duplex by its Ligand
    Monserud, Jon H.
    Macri, Katherine M.
    Schwartz, Daniel K.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (44) : 13710 - 13713
  • [48] Toehold-mediated DNA strand displacement-driven super-fast tripedal DNA walker for ultrasensitive and label-free electrochemical detection of ochratoxin A
    Wang, Yeru
    Wang, Yu
    Liu, Su
    Sun, Wenyu
    Zhang, Manru
    Jiang, Long
    Li, Minghan
    Yu, Jinghua
    Huang, Jiadong
    ANALYTICA CHIMICA ACTA, 2021, 1143 : 21 - 30
  • [49] A dual-cycling biosensor for target DNA detection based on the toehold-mediated strand displacement reaction and exonuclease III assisted amplification
    Ling, Yu
    Zhang, Xiao Fang
    Chen, Xiao Hui
    Liu, Li
    Wang, Xiao Hu
    Wang, De Shou
    Li, Nian Bing
    Luo, Hong Qun
    NEW JOURNAL OF CHEMISTRY, 2018, 42 (06) : 4714 - 4718
  • [50] Rapid bacteria electrochemical sensor based on cascade amplification of 3D DNA walking machine and toehold-mediated strand displacement
    Zhang, Jialin
    Liu, Wenjing
    Li, Jinhui
    Lu, Kangqiang
    Wen, Herui
    Ren, Jiali
    TALANTA, 2022, 249
12345