Fine and bidirectional regulation of toehold-mediated DNA strand displacement by a wedge-like DNA tool

被引：11
|
作者：
Li, Longjie [1 ,2 ]
Zhang, Wenkai [1 ,3 ]
Tang, Xiaofeng [1 ]
Li, Zejian [1 ]
Wu, Yuzhou [2 ]
Xiao, Xianjin [1 ,3 ]
机构：
[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Inst Reprod Hlth, Wuhan 430030, Peoples R China
[2] Huazhong Univ Sci & Technol, Hubei Key Lab Bioinorgan Chem & Mat Med, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China
[3] Huazhong Univ Sci & Technol, Dept Obstet & Gynaecol, Union Hosp, Tone Med Coll, Wuhan 430022, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 62期
基金：
中国国家自然科学基金;
关键词：
CIRCUITS; SWITCHES; KINETICS;
D O I：
10.1039/d0cc03722b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A wedge-like tool was established to finely and bidirectionally regulate the displacement rate of toehold-mediated strand displacement. This novel tool is very robust in terms of sequence generality and is compatible with most of the current DNA nanodevices based on traditional toehold reactions.
引用
收藏
页码：8794 / 8797
页数：4
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