Dynamic monitoring of an enzymatically driven dissipative toehold-mediated strand displacement reaction

被引：1
|
作者：
Li, Shuang [1 ]
Zhao, Disong [1 ]
Yang, Fangfang [1 ]
Liu, Shufeng [1 ]
机构：
[1] Yantai Univ, Coll Chem & Chem Engn, 30 Qingquan Rd, Yantai 264005, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 05期
基金：
中国国家自然科学基金;
关键词：
Substitution reactions;
D O I：
10.1039/d3cc05061k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A general strategy to program self-resettable and dissipative toehold-mediated strand displacement reactions was proposed, using DNA strands as the fuel and lambda exonuclease as the fuel-consuming unit. This non-equilibrium system is reversible and temporally controllable. Furthermore, it can be well integrated into a DNA network to temporally control its cascade reaction or dynamic behaviour. A general strategy to program self-resettable and dissipative toehold-mediated strand displacement reactions by lambda exonuclease was proposed.
引用
收藏
页码：570 / 573
页数：4
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