New strategies for electrochemical nucleic acid detection

被引:0
|
作者
Popovich, Natasha D. [1 ]
Thorp, H. Holden [2 ]
机构
[1] Home Diagnostics Inc., Fort Lauderdale, FL, United States
[2] University of NC at Chapel Hill, Chapel Hill, NC, United States
来源
Electrochemical Society Interface | 2002年 / 11卷 / 04期
关键词
Nucleic acid detection;
D O I
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中图分类号
学科分类号
摘要
Latest strategies for electrochemical nucleic acid detection were discussed. Hybridization-based assays for single-base mismatch detection were typically limited in sensitivity by the difference in melting temperature between the duplex and the one with a single defect. Electrochemical sensors for nucleic acids offered the prospects of lower limits of detection, greater miniaturization, and the elimination of optics.
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页码:30 / 34
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