New strategies for electrochemical nucleic acid detection

被引：0
|
作者：
Popovich, Natasha D. [1 ]
Thorp, H. Holden [2 ]
机构：
[1] Home Diagnostics Inc., Fort Lauderdale, FL, United States
[2] University of NC at Chapel Hill, Chapel Hill, NC, United States
来源：
Electrochemical Society Interface | 2002年 / 11卷 / 04期
关键词：
Nucleic acid detection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Latest strategies for electrochemical nucleic acid detection were discussed. Hybridization-based assays for single-base mismatch detection were typically limited in sensitivity by the difference in melting temperature between the duplex and the one with a single defect. Electrochemical sensors for nucleic acids offered the prospects of lower limits of detection, greater miniaturization, and the elimination of optics.
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页码：30 / 34
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