SYNTHESIS OF ENANTIOMERICALLY PURE BETA-AMINO AND GAMMA-AMINO-ACIDS FROM ASPARTIC AND GLUTAMIC-ACID DERIVATIVES

被引：0

作者：

ELMARINI, A

ROUMESTANT, ML

VIALLEFONT, P

RAZAFINDRAMBOA, D

BONATO, M

FOLLET, M

机构：

[1] UNIV MONTPELLIER SCI & TECH LANGUEDOC 2,URA 468,PL E BATAILLON,F-34095 MONTPELLIER 5,FRANCE

[2] SOC EXPANSIA,F-30390 ARAMON,FRANCE

来源：

SYNTHESIS-STUTTGART | 1992年 / 11期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of enantiomerically pure beta- and gamma-amino acids starting from commercially available aspartic and glutamic acid derivatives is described. The acid function, alpha to the amino group, is first transformed to a good leaving group and the product reacted with organocuprates to yield beta- and gamma-amino esters. After deprotection beta- and gamma-amino acids are obtained in good overall yields.

引用

页码：1104 / 1108

页数：5

共 50 条

[41] SYNTHESIS OF ENANTIOMERICALLY PURE GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID USING MALIC-ACID AS THE CHIRAL PRECURSOR
RAJASHEKHAR, B
KAISER, ET
JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (26): : 5480 - 5484
[42] BETA-AMINO ACIDS DERIVED FROM THIONAPHTHENE
MAMAEV, VP
SHKURKO, OP
ZHURNAL OBSHCHEI KHIMII, 1961, 31 (10): : 3288 - &
[43] SYNTHESIS OF OPTICALLY-ACTIVE ALPHA,BETA-DISUBSTITUTED BETA-AMINO NITRILES AND BETA-AMINO ACIDS STARTING FROM ASPARAGINE
GMEINER, P
HUMMEL, E
HAUBMANN, C
LIEBIGS ANNALEN, 1995, (11): : 1987 - 1992
[44] FORMATION OF ALPHA-AMINO-ACIDS FROM BETA-AMINO ACIDS AND GAMMA-AMINO ACIDS BY CONTACT GLOW-DISCHARGE ELECTROLYSIS
SUZUKI, S
TAMURA, M
TERASAWA, J
HARADA, K
BIOORGANIC CHEMISTRY, 1978, 7 (01) : 111 - 113
[45] ASYMMETRIC SYNTHESES OF BETA-AMINO ACID AND ASPARTIC-ACID BY REFORMATSKY REACTION
FURUKAWA, M
OKAWARA, T
NOGUCHI, Y
TERAWAKI, Y
CHEMICAL & PHARMACEUTICAL BULLETIN, 1978, 26 (01) : 260 - 263
[46] USE OF BENZYLPENICILLINACYLASE FROM ESCHERICHIA-COLI IN RESOLUTION OF SOME RACEMIC BETA-AMINO-ACIDS, GAMMA-AMINO-ACIDS, DELTA-AMINO-ACIDS AND EPSILON-AMINO-ACIDS
ROSSI, D
LUCENTE, G
ROMEO, A
EXPERIENTIA, 1977, 33 (12): : 1557 - 1559
[47] THE USE OF THE REFORMATSKY REACTION FOR THE SYNTHESIS OF BETA-AMINO ACIDS
BELLASSOUED, M
AROUSCHTARA, R
GAUDEMAR, M
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1982, 231 (03) : 185 - 189
[48] Chiral relay auxiliary for the synthesis of enantiomerically pure α-amino acids
Bull, SD
Davies, SG
Epstein, SW
Ouzman, JVA
CHEMICAL COMMUNICATIONS, 1998, (06) : 659 - 660
[49] Synthesis and therapeutic application of beta-amino alcohol derivatives
Boumzour, Wiame
El Youssfi, Safaa
El Hammoumi, Mohamed Merouane
Maazouz, Oussama
Nassri, Aziz
El Bachiri, Abdelhadi
JOURNAL OF MOLECULAR STRUCTURE, 2025, 1321
[50] THE SYNTHESIS OF BETA-AMINO ACIDS FROM AROMATIC HYDROXY AND ALKOXY ALDEHYDES
RODIONOV, VM
DUDINSKAYA, AA
AVRAMENKO, VG
SUVOROV, NN
ZHURNAL OBSHCHEI KHIMII, 1958, 28 (08): : 2242 - 2246

← 1 2 3 4 5 →