SYNTHESIS OF ENANTIOMERICALLY PURE BETA-AMINO AND GAMMA-AMINO-ACIDS FROM ASPARTIC AND GLUTAMIC-ACID DERIVATIVES

被引：0
|
作者：
ELMARINI, A
ROUMESTANT, ML
VIALLEFONT, P
RAZAFINDRAMBOA, D
BONATO, M
FOLLET, M
机构：
[1] UNIV MONTPELLIER SCI & TECH LANGUEDOC 2,URA 468,PL E BATAILLON,F-34095 MONTPELLIER 5,FRANCE
[2] SOC EXPANSIA,F-30390 ARAMON,FRANCE
来源：
SYNTHESIS-STUTTGART | 1992年 / 11期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of enantiomerically pure beta- and gamma-amino acids starting from commercially available aspartic and glutamic acid derivatives is described. The acid function, alpha to the amino group, is first transformed to a good leaving group and the product reacted with organocuprates to yield beta- and gamma-amino esters. After deprotection beta- and gamma-amino acids are obtained in good overall yields.
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页码：1104 / 1108
页数：5
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