A ONE-POT SYNTHESIS OF 8-BENZYL-4-METHYL-2H,10H-BENZO[1,2-B 3,4-B']DIPYRAN-2,10-DIONE

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作者
KHAN, MSY
SHARMA, P
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O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A convenient one-pot synthesis of the title compound(I) has been achieved by reacting 8-acetyl-7-hydroxy-4-methylcoumarin in acetone solution with phenylacetyl chloride in the presence of potassium carbonate with an yield of 42%. A preliminary pharmacological testing of the compound on perfused frog heart shows a Digitalis glycosides-like action.
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页码:477 / 478
页数:2
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