REFORMATSKY REACTION OF ETHYL 4-CHLORO-4,4-DIFLUOROCROTONATE - PREPARATION OF ALPHA-SUBSTITUTED 4,4-DIFLUORO-3-BUTENOATES

被引：0

作者：

TSUKAMOTO, T ^{[1
]}

KITAZUME, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT BIOENGN,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN

来源：

SYNLETT | 1992年 / 12期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reformatsky reagent derived from ethyl 4-chloro-4,4-difluorocrotonate was found to react with carbonyl compounds in the a-mode by using Zn-Cu couple to afford alpha-substituted 4,4-difluoro-3-butenoates.

引用

页码：977 / 979

页数：3

共 50 条

[41] REACTIONS OF POLYHALOFUNCTIONAL COMPOUNDS WITH METALS AND ELECTROPHILIC REAGENTS .20. STUDY OF THE REACTION OF ETHYL-ESTERS OF 4,4-DIHALO-2,2-DIMETHYL-3-HYDROXOALKANOIC ACIDS WITH ZINC AND ALPHA-CHLOROETHERS
SHCHEPIN, VV
GLADKOVA, GE
GESS, IB
ZHURNAL ORGANICHESKOI KHIMII, 1993, 29 (03): : 486 - 490
[42] ALPHA HALOGEN THIETANE S,S-DIOXIDE - ELIMINATION OF HALOGEN HYDRIC ACID IN 2-CHLORO-3-MORPHOLINO-4,4'-DIMETHYLTHIETANE S,S-DIOXIDE
MAIORANA, S
PAGANI, G
CHIMICA & L INDUSTRIA, 1971, 53 (03): : 261 - &
[43] THE REACTION BETWEEN CARBON-DISULFIDE AND SOME ALPHA-METHYLAMINONITRILES - THE SUPPOSED ISOMERISM OF 4,4-DIALKYL-5-IMINO-3-METHYLTHIAZOLIDINE-2-THIONES
CHUBB, FL
EDWARD, JT
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1981, 59 (18): : 2724 - 2728
[44] Preparation of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene) acetamide derivatives as novel arginine vasopressin V2 receptor agonists
Tsukamoto, Issei
Koshio, Hiroyuki
Akamatsu, Seijiro
Kuramochi, Takahiro
Saitoh, Chikashi
Yatsu, Takeyuki
Yanai-Inamura, Hiroko
Kitada, Chika
Yamamoto, Eisaku
Sakamoto, Shuichi
Tsukamoto, Shin-ichi
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (21) : 9524 - 9535
[45] THE PREPARATION OF METHYL AND ETHYL BETA-AMINO-ALPHA-(N-SUBSTITUTED-BENZIMIDOYL)CROTONATES, AND THEIR CONVERSION INTO METHYL AND ETHYL 3-METHYL-1-5-DIPHENYLPYRAZOLE-4-CARBOXYLATES
STASKUN, B
STEPHEN, H
JOURNAL OF THE CHEMICAL SOCIETY, 1956, (NOV): : 4696 - 4697
[46] Antitumor activity of 2-amino-4,4 alpha-dihydro-4 alpha,7-dimethyl-3H-phenoxazine-3-one, a novel phenoxazine derivative produced by the reaction of 2-amino-5-methylphenol with bovine hemolysate
Ishida, R
Yamanaka, S
Kawai, H
Ito, H
Iwai, M
Nishizawa, M
Hamatake, M
Tomoda, A
ANTI-CANCER DRUGS, 1996, 7 (05) : 591 - 595
[47] SYNTHESIS AND REACTION OF ALPHA,ALPHA-BIS(PHENYLTHIO)-GAMMA-BUTYROLACTONE - CONVENIENT METHOD FOR PREPARATION OF 3-SUBSTITUTED 2-BUTEN-4-OLIDE
WATANABE, M
SHIRAI, K
KUMAMOTO, T
CHEMISTRY LETTERS, 1975, (08) : 855 - 858
[48] Aqua complex of iron(III) and 5-chloro-3-(2-(4,4-dimethyl-2,6-dioxocyclohexylidene)hydrazinyl)-2-hydroxybenzenesulfonate: Structure and catalytic activity in Henry reaction
Mahmudov, Kamran T.
Kopylovich, Maximilian N.
Haukka, Matti
Mahmudova, Gunay S.
Esmaeila, Espandi F.
Chyragov, Famil M.
Pombeiro, Armando J. L.
JOURNAL OF MOLECULAR STRUCTURE, 2013, 1048 : 108 - 112
[49] THE PREPARATION OF SUBSTITUTED 5,6-DIHYDRO-2H-PYRANS AND 3,6-DIHYDRO-2H-PYRANS FROM 4,4-DIMETHYL-4-PHENYL-1,3-DIOXANES AND 4-METHYL-4-PHENYL-1,3-DIOXANES AND CARBONYL-COMPOUNDS
ROMANOV, NA
KANTOR, EA
MUSAVIROV, RS
KARAKHANOV, RA
RAKHMANKULOV, DL
ZHURNAL ORGANICHESKOI KHIMII, 1981, 17 (08): : 1762 - 1767
[50] SYNTHESIS OF 4,4-DIALKYL-1-IODO-3-BUTEN-2-ONES BY THE REACTION OF TERTIARY ALPHA-ALLENIC ALCOHOL CARBAMATES WITH N-IODOSUCCINIMIDE AND AQUEOUS SODIUM-BICARBONATE
FRIESEN, RW
PHIPPS, LG
SYNLETT, 1991, (06) : 420 - 422

← 1 2 3 4 5 →