REFORMATSKY REACTION OF ETHYL 4-CHLORO-4,4-DIFLUOROCROTONATE - PREPARATION OF ALPHA-SUBSTITUTED 4,4-DIFLUORO-3-BUTENOATES

被引：0
|
作者：
TSUKAMOTO, T [1 ]
KITAZUME, T [1 ]
机构：
[1] TOKYO INST TECHNOL,DEPT BIOENGN,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN
来源：
SYNLETT | 1992年 / 12期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reformatsky reagent derived from ethyl 4-chloro-4,4-difluorocrotonate was found to react with carbonyl compounds in the a-mode by using Zn-Cu couple to afford alpha-substituted 4,4-difluoro-3-butenoates.
引用
收藏
页码：977 / 979
页数：3
相关论文
共 50 条
  • [31] REACTIONS WITH ALPHA-SUBSTITUTED BETA-PROPIOLACTONES .1. 4,4-DISUBSTITUTED 2-OXAZOLIDINONES - RESEARCH ON COMPOUNDS ACTIVE ON CENTRAL NERVOUS SYSTEM .23.
    NICOLAUS, BI
    GALLO, G
    TESTA, E
    MARIANI, L
    JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (07): : 2253 - &
  • [32] Ethyl ({5-[5'-(2-ethoxy-2-oxoethoxy)-4,4''-difluoro-1,1':3',1''-terphenyl-4'-yl]1,3,4-oxadiazol-2-yl}sulfanyl)acetate
    Fun, Hoong-Kun
    Arshad, Suhana
    Samshuddin, S.
    Narayana, B.
    Sarojini, B. K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O674 - U1895
  • [33] MEYERS REACTION - USE OF 4,4-DIMETHYL-2-OXAZOLINES IN PREFERENCE TO 1-DIHYDRO-3-OXAZINES IN SYNTHESIS OF SUBSTITUTED KETONES
    DUBOIS, JE
    LION, C
    COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1972, 274 (03): : 303 - &
  • [34] Synthesis and crystal structure of ethyl 7-chloro-3-amino-9-(4-bromophenyl)thieno-[3,2-b]benzothiazine 4,4-dioxide 2-carboxylate
    Charris, Jaime
    Barazarte, Arthur
    Ferrer, Rosa
    Camacho, Jos
    Gamboa, Neira
    Rodrigues, Juan
    Atencio, Reinaldo
    Gonzalez, Teresa
    JOURNAL OF CHEMICAL RESEARCH-S, 2007, (01): : 16 - 18
  • [35] PYRROLE DERIVATIVES .16. REACTION OF 1-AMINO-1-DEOXY-D-FRUCTOSE WITH ETHYL 4,4-DIETHOXY-3-OXOBUTANOATE
    GARCIAGONZALEZ, F
    FERNANDE.J
    ALCUDIA, F
    ANALES DE QUIMICA-INTERNATIONAL EDITION, 1972, 68 (5-6): : 571 - +
  • [36] PYRROLE DERIVATIVES .14. REACTION OF 2-AMINO-2-DEOXY-D-GLUCOSE WITH ETHYL 4,4-DIETHOXY-3-OXOBUTANOATE
    GARCIAGONZALEZ, F
    FERNANDE.J
    ALCUDIA, F
    ANALES DE QUIMICA-INTERNATIONAL EDITION, 1971, 67 (04): : 383 - +
  • [37] Formal [3+3] cyclocondensations of 1,3-bis(silyloxy)-1,3-butadienes with 1-chloro-1,1-difluoro-4,4-dimethoxybut-3-en-2-one and 1,1-difluoro-4,4-dimethoxybut-3-en-2-one. Regioselective synthesis of fluorinated salicylates and pyran-4-ones
    Reimann, Sebastian
    Bunescu, Alina
    Litschko, Robert
    Erfle, Silke
    Domke, Lutz
    Bendrath, Franziska
    Abilov, Zharylkasyn A.
    Spannenberg, Anke
    Villinger, Alexander
    Langer, Peter
    JOURNAL OF FLUORINE CHEMISTRY, 2012, 139 : 28 - 45
  • [38] REACTION OF PERIODATE FISSION OF 2-CHLORO-3-(N,N-DIMETHYLAMINO)-4,4-DIMETHOXY-5-ALLYLCYCLOPENT-2-EN-1-ONE
    TOLSTIKOV, GA
    ISMAILOV, SA
    PRISHCHEPOVA, EV
    AKBUTINA, FA
    MIFTAKHOV, MS
    ZHURNAL ORGANICHESKOI KHIMII, 1990, 26 (08): : 1801 - 1803
  • [39] RADIATION-INDUCED AND ELECTROCHEMICAL FORMATION OF 3-SUBSTITUTED 4,4-DIMETHYL-GAMMA-BUTYROLACTONE FROM ALPHA,BETA-UNSATURATED ESTER
    ITOH, M
    TAGUCHI, T
    SUZUKI, A
    TOKUDA, M
    CHUNG, VV
    JOURNAL OF ORGANIC CHEMISTRY, 1972, 37 (14): : 2357 - &
  • [40] HALOGENT REPLACEMENT IN AZOCOMPOUNDS .13. REPLACEMENT OF CHLORO GROUP BY ALKOXY- AND ARYLOXY GROUPS IN BISAZO DYESTUFFS DERIVED FROM 3,3'-DICHLOROBENZIDINE AND PREPARATION OF 4,4'-DIAMINO-3,3'-DIHYDROXYBIPHENYL ETHERS
    ROZANELSKAYA, N
    STEPANOV, BI
    ZHURNAL OBSHCHEI KHIMII, 1961, 31 (03): : 758 - &
12345